Naqvi Syed Atif Hasan, Farhan Muhammad, Ahmad Muhammad, Kiran Rafia, Shahbaz Muhammad, Abbas Aqleem, Hakim Fahad, Shabbir Muhammad, Tan Yee Shin, Sathiya Seelan Jaya Seelan
Department of Plant Pathology, Faculty of Agricultural Sciences and Technology, Bahauddin Zakariya University, 60800, Multan, Pakistan.
Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah, Jalan, UMS, 88400, Kota Kinabalu, Sabah, Malaysia.
Arch Microbiol. 2025 Jan 10;207(2):31. doi: 10.1007/s00203-024-04219-6.
The agricultural productivity and world-wide food security is affected by different phytopathogens, in which Fusarium is more destructive affecting more than 150 crops, now got resistance against many fungicides that possess harmful effects on environment such as soil health, air pollution, and human health. Fusarium fungicide resistance is an increasing concern in agricultural and environmental contexts, requiring a thorough understanding of its causes, implications, and management approaches. The mechanisms of fungicide resistance in Fusarium spp., are reviewed in this article, including increased efflux pump activity, target-site mutations, and metabolic detoxification pathways. Fusarium is naturally resistant to some of the fungicides, on the other hand; it speedily develops resistance against the other fungicides groups. Most of the important plant pathogenic Fusarium species including F. oxysporum, F. psedogramanium, F. graminearium and Fusarium solani, which have shown resistance to major groups of fungicides including triazoles, phenylpyrole and benzimedazoles in various regions of the world. The review also covers a range of management techniques, including fungicide rotation, resistant cultivars, cultural methods, and biological control agents, to lessen fungicide resistance. By shedding light on the current state of knowledge concerning fungicide resistance in Fusarium spp., this review provides valuable information to researchers, policymakers, and practitioners to design long-term effective disease management approaches, as well as fungal menace control to preserve fungicides' effectiveness in agriculture and conservancy activities.
农业生产力和全球粮食安全受到不同植物病原体的影响，其中镰刀菌的破坏力更强，能影响150多种作物，目前它已对许多对环境有有害影响（如土壤健康、空气污染和人类健康）的杀菌剂产生了抗性。镰刀菌对杀菌剂的抗性在农业和环境领域日益受到关注，需要深入了解其成因、影响及管理方法。本文综述了镰刀菌属中杀菌剂抗性的机制，包括外排泵活性增加、靶位点突变和代谢解毒途径。另一方面，镰刀菌对某些杀菌剂具有天然抗性；它能迅速对其他杀菌剂类别产生抗性。大多数重要的植物病原镰刀菌物种，包括尖孢镰刀菌、拟枝孢镰刀菌、禾谷镰刀菌和茄病镰刀菌，在世界不同地区已对包括三唑类、苯吡咯类和苯并咪唑类在内的主要杀菌剂类别表现出抗性。该综述还涵盖了一系列管理技术，包括杀菌剂轮换、抗性品种、栽培方法和生物防治剂，以减轻杀菌剂抗性。通过阐明镰刀菌属中杀菌剂抗性的当前知识状况，本综述为研究人员、政策制定者和从业者提供了有价值的信息，以设计长期有效的病害管理方法，以及控制真菌威胁，以保持杀菌剂在农业和保护活动中的有效性。
