Guzmán-Castellanos Karen Berenice, Zazpe Itziar, Santiago Susana, Bes-Rastrollo Maira, Martínez-González Miguel Ángel
Department of Preventive Medicine and Public Health, School of Medicine-Clínica Universidad de Navarra, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.
Department of Nutrition and Food Sciences and Physiology, University of Navarra, Irunlarrea 1, 31008 Pamplona, Spain.
Nutrients. 2024 Dec 25;17(1):27. doi: 10.3390/nu17010027.
BACKGROUND/OBJECTIVES: Noncommunicable diseases, particularly cardiovascular disease (CVD), represent a significant global public health challenge, with unhealthy diets as a major risk factor. This study investigates the association between adherence to the Planetary Health Diet proposed by the EAT-Lancet Commission and CVD risk.
Utilizing data from the Seguimiento Universidad de Navarra (SUN) cohort, which included 18,656 participants (mean age 38 years; 61% women), we assessed dietary intake using a validated food frequency questionnaire and the Planetary Health Diet Index to evaluate adherence (range 0-42). CVD was defined as new-onset stroke, myocardial infarction, or CVD death.
After a median follow-up time of 11.5 years, 220 cases of CVD were identified. Higher adherence to the Planetary Health Diet revealed no statistically significant reduction in CVD risk associated with the diet. Cox proportional hazard models indicated a trend towards lower CVD risk in the highest adherence quartile, but this did not reach significance (HR 0.77, 95% CI 0.51-1.18, p-trend = 0.127). Sensitivity analyses corroborated these results. Discrepancies in previous studies highlight the complexity of dietary assessments and underscore the need for standardized scoring systems.
In a large Spanish cohort, adherence to the Planetary Health Diet showed no significant reduction in CVD risk. Further research is needed to reach a consensus on the operational definition of the Planetary Health Diet and to clarify the relationship between diet and CVD risk.
背景/目的:非传染性疾病,尤其是心血管疾病(CVD),是一项重大的全球公共卫生挑战,不健康饮食是主要风险因素。本研究调查遵循EAT-柳叶刀委员会提出的“行星健康饮食”与心血管疾病风险之间的关联。
利用纳瓦拉大学随访(SUN)队列的数据,该队列包括18656名参与者(平均年龄38岁;61%为女性),我们使用经过验证的食物频率问卷和行星健康饮食指数评估饮食摄入量,以评估遵循程度(范围0-42)。心血管疾病定义为新发中风、心肌梗死或心血管疾病死亡。
在中位随访时间11.5年后,确定了220例心血管疾病病例。较高程度地遵循行星健康饮食并未显示出与该饮食相关的心血管疾病风险有统计学意义的降低。Cox比例风险模型表明,在最高遵循四分位数中,心血管疾病风险有降低趋势,但未达到显著水平(风险比0.77,95%置信区间0.51-1.18,p趋势=0.127)。敏感性分析证实了这些结果。先前研究中的差异凸显了饮食评估的复杂性,并强调了标准化评分系统的必要性。
在一个大型西班牙队列中,遵循行星健康饮食并未显示出心血管疾病风险有显著降低。需要进一步研究以就行星健康饮食的操作定义达成共识,并阐明饮食与心血管疾病风险之间 的关系。