Suppr超能文献

类风湿关节炎女性的孕前咨询:风险、评估及多学科方法指南

Pre-Pregnancy Counselling for Women with Rheumatoid Arthritis: A Guide on Risks, Evaluations, and Multidisciplinary Approaches.

作者信息

Saulescu Ioana Cristina, Panaitescu Anca Maria, Gică Nicolae, Grădinaru Elena, Opris-Belinski Daniela

机构信息

Department of Internal Medicine and Rheumatology, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.

Department of Internal Medicine and Rheumatology, Sfanta Maria Hospital, 011172 Bucharest, Romania.

出版信息

J Clin Med. 2024 Dec 28;14(1):114. doi: 10.3390/jcm14010114.

Abstract

This paper explores the essential role of pre-pregnancy counselling for women with rheumatoid arthritis (RA), focusing on minimising risks and optimising pregnancy outcomes. RA, a prevalent inflammatory arthritis with onset during childbearing years, necessitates targeted preconception counselling to manage disease activity and comorbidities effectively. The counselling ensures medication compatibility and planning around disease flares, and it involves a multidisciplinary team comprising rheumatologists, obstetricians, and other specialists to develop individualised care plans. This literature review highlights the challenges women with RA face, including prolonged time to pregnancy, increased risks during pregnancy, such as hypertension and preeclampsia, and potential fertility issues related to medication and disease activity. Emphasis is placed on the importance of assessing autoantibody presence and managing specific joint involvements that may affect anaesthetic procedures during pregnancy. This paper underscores the importance of timing conception during periods of low disease activity and adopting a "Treat-to-Target" approach using acceptable medications to maintain disease remission. This study calls for routine family planning discussions and preconception evaluations to address reproductive health and treatment plans, thereby supporting women with RA in achieving favourable pregnancy outcomes comparable to the general population. The multidisciplinary approach and regular counselling are critical to navigating the complexities of RA and pregnancy successfully.

摘要

本文探讨了孕前咨询对类风湿关节炎(RA)女性的重要作用,重点在于将风险降至最低并优化妊娠结局。RA是一种常见的炎症性关节炎,在育龄期发病,需要有针对性的孕前咨询,以有效控制疾病活动和合并症。咨询可确保药物兼容性,并围绕疾病发作进行规划,且涉及由风湿病学家、产科医生和其他专家组成的多学科团队,以制定个性化的护理计划。这篇文献综述强调了RA女性面临的挑战,包括怀孕时间延长、孕期风险增加,如高血压和先兆子痫,以及与药物和疾病活动相关的潜在生育问题。重点在于评估自身抗体的存在以及处理可能影响孕期麻醉程序的特定关节受累情况的重要性。本文强调了在疾病活动度较低的时期受孕的重要性,并采用“达标治疗”方法,使用可接受的药物维持疾病缓解。这项研究呼吁进行常规的计划生育讨论和孕前评估,以解决生殖健康和治疗计划问题,从而支持RA女性实现与普通人群相当的良好妊娠结局。多学科方法和定期咨询对于成功应对RA和妊娠的复杂性至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e3a/11722274/7f88b3b878ac/jcm-14-00114-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验