Pierreux Stijn, Hatem Samar M, Roggeman Stijn, Schiltz Marc
Department of Physical and Rehabilitation Medicine, Universitair Ziekenhuis Brussel.
Stimulus Research Group, Vrije Universiteit Brussel.
J Rehabil Med Clin Commun. 2025 Jan 3;8:41323. doi: 10.2340/jrm-cc.v8.41323. eCollection 2025.
Heterotopic ossification is a common complication after joint replacement surgery, such as hip or knee arthroplasty. In the intensive care unit, it is most commonly associated with traumatic brain injury or spinal cord injury. To prevent recurrence, surgical resection of heterotopic ossification is recommended once the ectopic bone has fully matured, which is estimated to occur after at least 12 months.
This case describes a young woman with no relevant previous medical history who developed severe bilateral heterotopic ossification on the anteromedial sides of her knees after an intensive care unit stay. Passive flexion of both knees was limited to 50°. X-ray was a simple diagnostic tool. Predisposing factors were extended immobilization, prolonged systematic inflammatory condition and mechanical ventilation. Due to the failure of initial conservative therapy, the heterotopic ossification was resected early, 4 months after onset of first symptoms. Following an intensive rehabilitation program, a normal, pain-free gait and full range of motion of both knees were achieved 9 months after surgery.
This case report demonstrates that early resection of heterotopic ossification can result in a good clinical and functional outcome.
异位骨化是关节置换手术后的常见并发症,如髋关节或膝关节置换术。在重症监护病房,它最常与创伤性脑损伤或脊髓损伤相关。为防止复发,一旦异位骨完全成熟,建议进行手术切除异位骨化,估计至少在12个月后发生。
本病例描述了一名既往无相关病史的年轻女性,在重症监护病房住院后,双侧膝关节前内侧出现严重的异位骨化。双膝被动屈曲受限至50°。X线是一种简单的诊断工具。诱发因素包括长期制动、长期系统性炎症状态和机械通气。由于初始保守治疗失败,在首次出现症状4个月后早期切除异位骨化。经过强化康复计划,术后9个月实现了正常、无痛的步态和双膝的全范围活动。
本病例报告表明,早期切除异位骨化可带来良好的临床和功能结果。