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股骨骨折患者脊髓麻醉前静脉注射右美托咪定和氯胺酮与股神经阻滞用于体位性疼痛的比较:一项前瞻性随机研究。

Comparison of intravenous dexmedetomidine and ketamine with femoral nerve block for positional pain before spinal anaesthesia in patients with fracture femur: A prospective randomised study.

作者信息

Ch V Jyotsna, Nikhar Sapna Annaji, Kar Akhya Kumar, Durga Padmaja

机构信息

Department of Anaesthesiology and Intensive Care, Nizam's Institute of Medical Sciences, Hyderabad, India.

Department of Anesthesiology, Nizam's Institute of Medical Sciences, Hyderabad, India.

出版信息

J Perioper Pract. 2025 Jan 13:17504589231224559. doi: 10.1177/17504589231224559.

Abstract

INTRODUCTION

Patient positioning for spinal anaesthesia in patients with femur fracture is extremely painful and various methods have been tried to reduce mobilisation pain.

AIM

To compare the analgesic efficacy of intravenous dexmedetomidine, ketamine and femoral nerve block in patients posted for fractured femur for alleviating the positional pain before spinal anaesthesia.

MATERIALS AND METHODS

A total of 75 patients (25 per group) of American Society of Anaesthetists Grade I-III patients of age group 18-80 years with fractured femur scheduled for elective surgery. All patients in Group C (n = 25) were given the femoral nerve block, Group D (n = 25) were given intravenous dexmedetomidine 0.5µg/kg and Group K (n = 25) were given intravenous ketamine 0.3mg/kg. The parameters assessed were quantitative relief of pain by a numerical rating scale and patient satisfaction score, quality of patient positioning and time to perform spinal anaesthesia along with hemodynamics and sedation score.

RESULTS

The pain scores and patient satisfaction scores were significantly decreased in all three groups but were much significantly lower in Group K.

CONCLUSION

Ketamine was found to be superior to the other two groups in terms of reducing positional pain.

摘要

引言

股骨骨折患者进行脊髓麻醉时的体位摆放极其疼痛,人们尝试了各种方法来减轻移动疼痛。

目的

比较静脉注射右美托咪定、氯胺酮和股神经阻滞对股骨骨折患者在脊髓麻醉前减轻体位疼痛的镇痛效果。

材料与方法

总共75例美国麻醉医师协会I - III级、年龄在18 - 80岁、计划进行择期手术的股骨骨折患者(每组25例)。C组(n = 25)所有患者接受股神经阻滞,D组(n = 25)患者静脉注射右美托咪定0.5µg/kg,K组(n = 25)患者静脉注射氯胺酮0.3mg/kg。评估的参数包括通过数字评分量表对疼痛的定量缓解、患者满意度评分、患者体位摆放质量、进行脊髓麻醉的时间以及血流动力学和镇静评分。

结果

三组患者的疼痛评分和患者满意度评分均显著降低,但K组显著更低。

结论

在减轻体位疼痛方面,氯胺酮被发现优于其他两组。

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