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1990年至2019年炎症性心肌病和心肌炎的全球负担及可归因风险因素

Global burden and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019.

作者信息

Wu Guilan, Xu Wenlin, Wu Shuyi, Guan Chengfu, Zhang Jinhua

机构信息

Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, 18 Daoshan Road, Fuzhou, 350001, China.

出版信息

Arch Public Health. 2025 Jan 13;83(1):11. doi: 10.1186/s13690-024-01473-4.

DOI:10.1186/s13690-024-01473-4
PMID:39806418
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11726952/
Abstract

BACKGROUND

Our understanding of the global burden distribution of inflammatory cardiomyopathy and myocarditis is very limited.

OBJECTIVE

To comprehensively assess the global burden distribution and attributable risk factors of inflammatory cardiomyopathy and myocarditis from 1990 to 2019.

METHODS

We extracted the data on death, disability-adjusted life years (DALY), and age-standardized rate (ASR) of inflammatory cardiomyopathy and myocarditis from the 2019 Global Burden of Disease (GBD) study, including the comprehensive data and the data classified by age/sex. Evaluate the epidemic trend by calculating the estimated annual percentage change (EAPC) of the above variables. This paper discusses the spatial differences from four aspects: global, five socio-demographic index regions, 21 GBD regions, and 204 countries and regions. We also estimated the risk factors attributable to inflammatory cardiomyopathy and myocarditis-related deaths.

RESULTS

In 2019, the global death toll from inflammatory cardiomyopathy and myocarditis was 340,349, and the age-standardized mortality rate (ASDR) was 4.40/100,000, of which the elderly and men were the majority. Although ASR has decreased in developed areas, inflammatory cardiomyopathy and myocarditis are still important health problems in those relatively underdeveloped areas. Similar DALYs burden pattern of inflammatory cardiomyopathy and myocarditis was also observed during the study period. Globally, among men over 60 and women over 65, the proportion of deaths caused by high systolic blood pressure in 2019 was higher than that in 1990.

CONCLUSIONS

Inflammatory cardiomyopathy and myocarditis are still important global public health problems. The changing pattern of the burden of inflammatory cardiomyopathy and myocarditis varies with location, age, and sex, so it is essential to improve resource allocation to formulate more effective and targeted prevention strategies. In addition, the control of blood pressure should be emphasized.

摘要

背景

我们对炎症性心肌病和心肌炎的全球负担分布了解非常有限。

目的

全面评估1990年至2019年炎症性心肌病和心肌炎的全球负担分布及可归因风险因素。

方法

我们从2019年全球疾病负担(GBD)研究中提取了炎症性心肌病和心肌炎的死亡、伤残调整生命年(DALY)及年龄标准化率(ASR)数据,包括综合数据以及按年龄/性别分类的数据。通过计算上述变量的估计年度百分比变化(EAPC)来评估流行趋势。本文从全球、五个社会人口指数区域、21个GBD区域以及204个国家和地区这四个方面探讨空间差异。我们还估计了炎症性心肌病和心肌炎相关死亡的可归因风险因素。

结果

2019年,全球炎症性心肌病和心肌炎死亡人数为340,349人,年龄标准化死亡率(ASDR)为4.40/10万,其中老年人和男性占多数。尽管发达地区的ASR有所下降,但炎症性心肌病和心肌炎在那些相对欠发达地区仍是重要的健康问题。在研究期间也观察到了炎症性心肌病和心肌炎类似的DALYs负担模式。在全球范围内,2019年60岁以上男性和65岁以上女性中,由高收缩压导致的死亡比例高于1990年。

结论

炎症性心肌病和心肌炎仍是重要的全球公共卫生问题。炎症性心肌病和心肌炎负担的变化模式因地点、年龄和性别而异,因此必须改善资源分配以制定更有效、更有针对性的预防策略。此外,应强调血压控制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/ff7cec0010d7/13690_2024_1473_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/c14d2563bf12/13690_2024_1473_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/7ce607f0cdee/13690_2024_1473_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/f31113f5bc34/13690_2024_1473_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/ff7cec0010d7/13690_2024_1473_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/c14d2563bf12/13690_2024_1473_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/7ce607f0cdee/13690_2024_1473_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/f31113f5bc34/13690_2024_1473_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1c6/11726952/ff7cec0010d7/13690_2024_1473_Fig3_HTML.jpg

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