Nagaraju Ganji Purnachandra, Sandhya Tatekalva, Srilatha Mundla, Ganji Swapna Priya, Saddala Madhu Sudhana, El-Rayes Bassel F
School of Medicine, Division of Hematology and Oncology, University of Alabama at Birmingham, Birmingham, AL, 35233, USA.
Department of Computer Science, Sri Venkateswara University, Tirupati, 517502, AP, India.
Cancer Lett. 2025 Mar 1;612:217461. doi: 10.1016/j.canlet.2025.217461. Epub 2025 Jan 12.
GI (Gastrointestinal) malignancies are one of the most common and lethal cancers globally. The dawn of precision medicine and developing technologies have reduced the mortality rates for GI malignancies, underscoring the main role of early detection methods for survival rate improvement. Artificial intelligence (AI) is a new technology that may improve GI cancer screening, treatment, and therapeutic efficiency for better patient care. AI could accelerate the development of targeted therapies by analyzing considerable data from the genome and identifying biomarkers connected with GI tumors. This opens up new avenues toward more tailored and personalized approaches, raising efficacy while reducing undesired side effects. For instance, AI may improve treatment outcomes by accurately predicting patient responses to therapeutic regimens, helping oncologists choose the most effective treatment options. This review will outline the transformative potential of AI in GI oncology by emphasizing the incorporation of AI-based technologies to enhance patient care.
胃肠道（GI）恶性肿瘤是全球最常见且致命的癌症之一。精准医学的兴起和技术的发展降低了胃肠道恶性肿瘤的死亡率，凸显了早期检测方法对提高生存率的主要作用。人工智能（AI）是一项新技术，它可能会改善胃肠道癌症的筛查、治疗及治疗效果，从而为患者提供更好的护理。人工智能可以通过分析来自基因组的大量数据并识别与胃肠道肿瘤相关的生物标志物，加速靶向治疗的开发。这为更具针对性和个性化的治疗方法开辟了新途径，在提高疗效的同时减少不良副作用。例如，人工智能可以通过准确预测患者对治疗方案的反应来改善治疗效果，帮助肿瘤学家选择最有效的治疗方案。本综述将强调基于人工智能的技术在胃肠道肿瘤学中的应用，以提升患者护理水平，从而概述人工智能在胃肠道肿瘤学中的变革潜力。
