Dos Santos Bruna, da Silva Naiara Mirelly Marinho, Mora Silvia Eugenia Vargas, Justo André Augusto, Schmidt Elizabeth Moreira Dos Santos, Takahira Regina Kiomi
Veterinarian, Programa de Pós-Graduação em Medicina Veterinária, Departamento de Clínica Veterinária, Faculdade de Medicina Veterinária e Zootecnia (FMVZ), Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), Botucatu, SP, Brazil.
Veterinarian, Resident, Programa de Residência em Medicina Veterinária - Enfermidades Parasitárias dos Animais, Departamento de Clínica Veterinária, FMVZ, UNESP, Botucatu, SP, Brazil.
Braz J Vet Med. 2024 Jan 13;46:e007724. doi: 10.29374/2527-2179.bjvm007724. eCollection 2024.
Intestinal parasites of the genus are the most prevalent in coproparasitological examinations and necropsies of dogs in Brazil. Although adult dogs often remain asymptomatic when infected, there is limited published information concerning the laboratory and clinical findings and severity of infection in symptomatic adult dogs. Therefore, this study aimed to characterize the clinical and laboratory findings of adult -infected dogs. Data were obtained by surveying the medical records of dogs treated at a University Veterinary Hospital from June 2009 to June 2019. Of 243 cases, 30 met the selection criteria. The most frequent clinical signs were diarrhea and hematochezia (13/30 each - 43.3%), and the most common laboratory findings were eosinophilia (13/30 - 43.3%), increased RDW (6/29 - 20.7%), and hypoalbuminemia (5/21 - 23.8%). Dogs with spp. presented an increased proportion of high RDW (P= 0.010) compared with non-parasitized dogs. Dogs with higher fecal egg scores (n= 18) showed significantly lower RBC (6.26 ± 0.64 7.24 ± 0.74 10/µL, P< 0.001) and albumin levels (2.8 ± 0.5 3.2 ± 0.4 g/dL, P= 0.021), and an increased eosinophil count (1.42 ± 0.95 0.58 ± 0.47 10/µL, P= 0.003) compared with the control group. Fecal egg scores exhibited a weak correlation with eosinophils (r = 0.42, P= 0.002) and a moderate correlation with RBC (r = -0.52, P< 0.001). In conclusion, despite relevant clinical signs, the laboratory findings were indicative of mild alterations in adult dogs, especially in those with lower scores of eggs in coproparasitological tests.
在巴西， 属的肠道寄生虫在犬类粪便寄生虫学检查和尸检中最为常见。尽管成年犬感染后通常无症状，但关于有症状成年犬感染的实验室检查和临床发现以及感染严重程度的公开信息有限。因此，本研究旨在描述成年感染犬的临床和实验室检查结果。通过查阅2009年6月至2019年6月在一所大学兽医医院接受治疗的犬类病历获取数据。在243例病例中，30例符合选择标准。最常见的临床症状是腹泻和便血（各13/30 - 43.3%），最常见的实验室检查结果是嗜酸性粒细胞增多（13/30 - 43.3%）、红细胞分布宽度增加（6/29 - 20.7%）和低白蛋白血症（5/21 - 23.8%）。与未感染寄生虫的犬相比，感染 属寄生虫的犬红细胞分布宽度高的比例增加（P = 0.010）。粪便虫卵评分较高的犬（n = 18）与对照组相比，红细胞计数显著降低（6.26 ± 0.64对7.24 ± 0.74×10⁶/µL，P < 0.001），白蛋白水平降低（2.8 ± 0.5对3.2 ± 0.4 g/dL，P = 0.021），嗜酸性粒细胞计数增加（1.42 ± 0.95对0.58 ± 0.47×10³/µL，P = 0.003）。粪便虫卵评分与嗜酸性粒细胞呈弱相关（r = 0.42，P = 0.002），与红细胞呈中度相关（r = -0.52，P < 0.001）。总之，尽管有相关临床症状，但实验室检查结果表明成年犬有轻度改变特别是在粪便寄生虫学检查中虫卵评分较低的犬。
