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科学背后的故事:关于呼吸道合胞病毒的发现

The Story behind the Science: On the discovery of respiratory syncytial virus.

作者信息

Casadevall Arturo, Roane Philip R, Shenk Thomas, Roizman Bernard

机构信息

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Department of Microbiology, Howard University College of Medicine, Washington, DC, USA.

出版信息

mBio. 2025 Mar 12;16(3):e0307424. doi: 10.1128/mbio.03074-24. Epub 2025 Jan 21.

DOI:10.1128/mbio.03074-24
PMID:39835804
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11898631/
Abstract

Respiratory syncytial virus (RSV) was discovered in 1956 by the laboratory of Robert Chanock after its isolation from children with upper respiratory infections. Here, we review the events leading to its discovery including its prior isolation as chimpanzee coryza virus and its subsequent association with human disease.

摘要

呼吸道合胞病毒(RSV)于1956年由罗伯特·钱诺克实验室从患有上呼吸道感染的儿童中分离出来后被发现。在此,我们回顾了导致其发现的事件,包括其先前作为黑猩猩鼻病毒被分离以及随后与人类疾病的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/1a3edbe1c514/mbio.03074-24.f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/fa84a8ef6915/mbio.03074-24.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/1a3edbe1c514/mbio.03074-24.f002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/fa84a8ef6915/mbio.03074-24.f001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/1a3edbe1c514/mbio.03074-24.f002.jpg

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Disease Severity of Respiratory Syncytial Virus Compared with COVID-19 and Influenza Among Hospitalized Adults Aged ≥60 Years - IVY Network, 20 U.S. States, February 2022-May 2023.≥60岁住院成人中呼吸道合胞病毒与新冠病毒和流感的疾病严重程度比较——IVY网络,美国20个州,2022年2月至2023年5月
MMWR Morb Mortal Wkly Rep. 2023 Oct 6;72(40):1083-1088. doi: 10.15585/mmwr.mm7240a2.
2
Respiratory Syncytial Virus Is the Leading Cause of United States Infant Hospitalizations, 2009-2019: A Study of the National (Nationwide) Inpatient Sample.呼吸道合胞病毒是美国婴儿住院治疗的主要原因,2009-2019 年:国家(全国)住院患者样本研究。
J Infect Dis. 2022 Aug 15;226(Suppl 2):S154-S163. doi: 10.1093/infdis/jiac120.
3
The Discovery of Reverse Transcriptase.
逆转录酶的发现。
Annu Rev Virol. 2016 Sep 29;3(1):29-51. doi: 10.1146/annurev-virology-110615-035556. Epub 2016 Jul 22.
4
Pillars Article: Virus Interference. I. The Interferon. Proc R Soc Lond B Biol Sci. 1957. 147: 258-267.支柱文章:病毒干扰。I. 干扰素。《伦敦皇家学会学报B辑:生物科学》。1957年。第147卷:第258 - 267页。
J Immunol. 2015 Sep 1;195(5):1911-20.
5
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J Exp Med. 1944 Feb 1;79(2):137-58. doi: 10.1084/jem.79.2.137.
6
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Science. 1949 Jan 28;109(2822):85-7. doi: 10.1126/science.109.2822.85.
8
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9
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Am Rev Respir Dis. 1963 Sep;88:SUPPL 181-97. doi: 10.1164/arrd.1963.88.3P2.181.
10
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