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科学背后的故事:关于呼吸道合胞病毒的发现

The Story behind the Science: On the discovery of respiratory syncytial virus.

作者信息

Casadevall Arturo, Roane Philip R, Shenk Thomas, Roizman Bernard

机构信息

Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

Department of Microbiology, Howard University College of Medicine, Washington, DC, USA.

出版信息

mBio. 2025 Mar 12;16(3):e0307424. doi: 10.1128/mbio.03074-24. Epub 2025 Jan 21.

Abstract

Respiratory syncytial virus (RSV) was discovered in 1956 by the laboratory of Robert Chanock after its isolation from children with upper respiratory infections. Here, we review the events leading to its discovery including its prior isolation as chimpanzee coryza virus and its subsequent association with human disease.

摘要

呼吸道合胞病毒(RSV)于1956年由罗伯特·钱诺克实验室从患有上呼吸道感染的儿童中分离出来后被发现。在此,我们回顾了导致其发现的事件,包括其先前作为黑猩猩鼻病毒被分离以及随后与人类疾病的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/29be/11898631/fa84a8ef6915/mbio.03074-24.f001.jpg

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