具有用于密码子通读活性的非规范生物合成基因簇的sp. CC302I的基因组序列草图
Draft genome sequence of sp. CC302I with non-canonical biosynthetic gene clusters for codon-readthrough activity.
作者信息
Trejo-Alarcon Luisa M, Cruz-Morales Pablo, Licona-Cassani Cuauhtémoc
机构信息
Industrial Genomics Laboratory, FEMSA Biotechnolgy Center, School of Engineering and Sciences, Tecnológico de Monterrey, Monterrey, México.
Novo Nordisk Foundation Center for Biosustainability, Danmarks Tekniske Universitet, Kongens Lyngby, Denmark.
出版信息
Microbiol Resour Announc. 2025 Feb 11;14(2):e0110924. doi: 10.1128/mra.01109-24. Epub 2025 Jan 21.
sp. CC302I was isolated from a highly oligothrophic environment. High-throughput screening shows high codon-readthrough activity for the isolate with no canonical biosynthetic gene cluster responsible. Here, we report the whole-genome assembly of sp. CC302I and a preliminary identification of biosynthetic gene clusters encoded in the genome.
菌株CC302I是从高度贫营养环境中分离出来的。高通量筛选显示，该分离株具有高密码子通读活性，且没有负责的典型生物合成基因簇。在此，我们报告了菌株CC302I的全基因组组装以及基因组中编码的生物合成基因簇的初步鉴定。
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