2024年在芬兰、德国、波兰、西班牙、英国的废水样本中检测到2型循环疫苗衍生脊髓灰质炎病毒（cVDPV2）：警钟敲响
Detection of circulating vaccine-derived poliovirus type 2 (cVDPV2) in wastewater samples: a wake-up call, Finland, Germany, Poland, Spain, the United Kingdom, 2024.
作者信息
Böttcher Sindy, Kreibich Julian, Wilton Thomas, Saliba Vanessa, Blomqvist Soile, Al-Hello Haider, Savolainen-Kopra Carita, Wieczorek Magdalena, Gad Beata, Krzysztoszek Arleta, Pintó Rosa M, Cabrerizo María, Bosch Albert, Saxentoff Eugene, Diedrich Sabine, Martin Javier
机构信息
Robert Koch Institute (RKI), Berlin, Germany.
Medicines and Healthcare products Regulatory Agency (MHRA), South Mimms (Potters Bar), United Kingdom.
出版信息
Euro Surveill. 2025 Jan;30(3). doi: 10.2807/1560-7917.ES.2025.30.3.2500037.
In 2024, circulating vaccine-derived poliovirus type 2 (cVDPV2) was detected in wastewater samples in Finland, Germany, Poland, Spain and the United Kingdom (UK). All strains were genetically linked, but sequence analysis showed high genetic diversity among the strains identified within individual wastewater sites and countries and an unexpected high genetic proximity among isolates from different countries. Taken together these results, with sequential samples having tested positive in various sites, a broader geographic distribution beyond positive sampling sites must be considered.
2024年，在芬兰、德国、波兰、西班牙和英国的污水样本中检测到2型循环疫苗衍生脊髓灰质炎病毒（cVDPV2）。所有毒株在基因上都有联系，但序列分析表明，在各个污水站点和国家内鉴定出的毒株之间存在高度的遗传多样性，而且来自不同国家的分离株之间存在意外的高遗传相似性。综合这些结果以及各个地点连续样本检测呈阳性的情况，必须考虑到阳性采样地点之外更广泛的地理分布。
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