Corti Emily J, Gasson Natalie, Grant Hayley, Wisniewski Brayden, Loftus Andrea M
School of Population Health, Curtin University, GPO Box U1987, Bentley, WA 6102, Australia.
Curtin Neuroscience Research Laboratory, Curtin University, GPO Box U1987, Bentley, WA 6102, Australia.
Brain Sci. 2025 Jan 13;15(1):66. doi: 10.3390/brainsci15010066.
BACKGROUND/OBJECTIVES: Objective memory decline is associated with poor quality of life (QOL) in Parkinson's disease (PD, but it is unclear what role perception of memory (metamemory) plays. The Multifactorial Memory Questionnaire (MMQ) measures metamemory and is proposed to have a three-factor structure, but the factor structure of the MMQ in PD has not been explored. The current study examined (i) the factor structure of the MMQ in PD and (ii) the relationship between the metamemory and QOL in PD.
This longitudinal, observational study involved 149 participants with PD (98 males, M age = 65.78 years, SD = 9.25). Participants completed the MMQ and the Unified Parkinson's Disease Rating Scale (disease severity) at baseline, and the Parkinson's Disease Questionnaire-39 (QOL) two years later.
Confirmatory factor analysis revealed both the three-factor and four-factor models were inadequate. Exploratory factor analysis resulted in a four-factor solution. The contentment and ability subscales from the original factor structure remained, while the strategies subscale was divided into external strategies and internal strategies. Disease severity, ability, and internal strategies uniquely predicted QOL. Individuals who reported low subjective memory ability and high use of internal strategies reported worse QOL two years later.
These findings indicate that metamemory predicts QOL in PD and suggest that improved perceived memory ability and strategy use could offer avenues for improved QOL.
背景/目的：在帕金森病（PD）中，客观记忆衰退与生活质量（QOL）较差相关，但记忆感知（元记忆）所起的作用尚不清楚。多因素记忆问卷（MMQ）用于测量元记忆，并且被认为具有三因素结构，但尚未探究其在PD中的因素结构。本研究考察了（i）MMQ在PD中的因素结构，以及（ii）PD中元记忆与QOL之间的关系。
这项纵向观察性研究纳入了149名PD患者（98名男性，平均年龄=65.78岁，标准差=9.25）。参与者在基线时完成MMQ和统一帕金森病评定量表（疾病严重程度），并在两年后完成帕金森病问卷-39（QOL）。
验证性因素分析表明三因素模型和四因素模型均不适用。探索性因素分析得到了一个四因素解决方案。原始因素结构中的满足感和能力分量表得以保留，而策略分量表被分为外部策略和内部策略。疾病严重程度、能力和内部策略可唯一预测QOL。报告主观记忆能力低且大量使用内部策略的个体在两年后生活质量较差。
这些发现表明元记忆可预测PD患者的QOL，并提示改善记忆感知能力和策略使用可能为提高QOL提供途径。
