Mendes Pedro Diogo, Santos Daniela, Meneses Maria, Gonçalves Fátima, Domingos Gonçalo Jantarada, Caneiras Cátia
Laboratory of Microbiology Research in Environmental Health (EnviHealthMicro Lab), Institute of Environmental Health (ISAMB), Associate Laboratory TERRA, Faculdade de Medicina, Universidade de Lisboa, 1249-028 Lisboa, Portugal.
Infectious Diseases Department, ULS Santa Maria, 1649-028 Lisboa, Portugal.
Trop Med Infect Dis. 2025 Jan 18;10(1):26. doi: 10.3390/tropicalmed10010026.
Globalization in the 21st century has posed several challenges. In particular, the spread of multidrug-resistant bacterial strains, especially Gram-negative bacteria, which are prevalent in certain regions of the world, is one of the most critical issues. This raises concerns about the risks associated with the booming tourism industry and migratory flows. In fact, even transient colonization with multidrug-resistant strains can present significant challenges to individual, family, and public health. Understanding the epidemiology and mechanisms of resistance, associated risk factors and prevention policies is therefore essential to ensure that strategies are in place to limit the global spread of high-risk bacterial clones and thereby protect public health.
21世纪的全球化带来了诸多挑战。特别是多重耐药细菌菌株的传播,尤其是革兰氏阴性菌,它们在世界某些地区很普遍,这是最关键的问题之一。这引发了人们对蓬勃发展的旅游业和移民潮所带来风险的担忧。事实上,即使是多重耐药菌株的短暂定植也会给个人、家庭和公共卫生带来重大挑战。因此,了解耐药性的流行病学和机制、相关风险因素及预防政策对于确保制定战略以限制高风险细菌克隆的全球传播从而保护公众健康至关重要。