Li Zonggang, Liu Chang, Shao Dongyan, Tan Chune, Cao Yingqi, Deng Senzhong, Lim Teng Teeh, Xu Fei
Beijing Key Laboratory of Detection Technology for Animal-Derived Food Safety, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Key Laboratory of Agricultural Engineering in Structure and Environment, the Ministry of Agriculture and Rural Affairs of the People's Republic of China, Beijing 100083, China.
Toxics. 2025 Jan 10;13(1):48. doi: 10.3390/toxics13010048.
Hypochlorous acid has been attempted as an additive to animal drinking water in practical animal farming processes for water microbial quality control. Despite its potential, there is still a knowledge gap concerning the effects of hypochlorous acid on both poultry growth performance and gut microbial load. To address this gap, an animal study was conducted using flow cytometry to quantify the age-related microbial load in broiler manure and gut contents. We observed that the effect on growth performance was sustained only during the starter phase, with no significant impact throughout the entire production cycle. The treatment could reduce the microbial load of both fresh broiler manure and cecal contents. Despite this convergence in the duodenum, significant differences in microbial loads between the control and treatment groups persisted in the manure and cecal contents throughout the later stages. Our findings demonstrate that consuming low-concentration hypochlorous acid water over the long term can lower the microbial load in the broiler gut throughout the entire growth cycle without impacting overall growth performance. Future research on drinking or feed additives should incorporate microbial absolute quantification methods to achieve a more precise assessment of microbiota.
在实际养殖过程中，次氯酸已被尝试用作动物饮用水的添加剂，以控制水质微生物。尽管具有潜力，但关于次氯酸对家禽生长性能和肠道微生物负荷的影响仍存在知识空白。为填补这一空白，进行了一项动物研究，使用流式细胞术量化肉鸡粪便和肠道内容物中与年龄相关的微生物负荷。我们观察到，对生长性能的影响仅在幼雏期持续存在，在整个生产周期中没有显著影响。该处理可降低新鲜肉鸡粪便和盲肠内容物的微生物负荷。尽管在十二指肠中出现了这种趋同现象，但在后期，对照组和处理组之间粪便和盲肠内容物的微生物负荷仍存在显著差异。我们的研究结果表明，长期饮用低浓度次氯酸水可在整个生长周期内降低肉鸡肠道中的微生物负荷，而不会影响整体生长性能。未来关于饮用水或饲料添加剂的研究应采用微生物绝对定量方法，以更精确地评估微生物群。
