Dong Rui, Wang Jing, Guan Ruiqi, Sun Jianwei, Jin Ping, Shen Junling
Yunnan Key Laboratory of Cell Metabolism and Diseases, Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650091, China.
State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming 650091, China.
Antioxidants (Basel). 2025 Jan 17;14(1):104. doi: 10.3390/antiox14010104.
Breast cancer is one of the most prevalent cancers worldwide. Recent studies have increasingly emphasized the role of oxidative stress in the initiation and progression of breast cancer. This article reviews how oxidative stress imbalance influences the occurrence and advancement of breast cancer, elucidating the intricate mechanisms through which reactive oxygen species (ROS) operate in this context and their potential therapeutic applications. By highlighting these critical insights, this review aims to enhance our understanding of oxidative stress as a potential target for innovative therapeutic strategies in the management of breast cancer.
乳腺癌是全球最常见的癌症之一。最近的研究越来越强调氧化应激在乳腺癌发生和发展中的作用。本文综述了氧化应激失衡如何影响乳腺癌的发生和进展，阐明了活性氧（ROS）在这种情况下发挥作用的复杂机制及其潜在的治疗应用。通过强调这些关键见解，本综述旨在增进我们对氧化应激的理解，将其作为乳腺癌管理中创新治疗策略的潜在靶点。
