Nesbitt J C, Moise K J, Sawyers J L
Arch Surg. 1985 May;120(5):636-40. doi: 10.1001/archsurg.1985.01390290110020.
Colorectal carcinoma in pregnancy is rare. The symptoms frequently are masked by the symptoms associated with normal pregnancy, resulting in delayed diagnosis. Based on our experience with five patients and review of the literature, we developed a management regimen that takes an aggressive approach to tumor excision, yet maintains the pregnancy and fertility if possible. The prognosis is poor for most patients because the stage of the tumor is usually advanced at the time of diagnosis. The key to improved survival, as with all cancers, is early diagnosis and treatment.
妊娠期结直肠癌较为罕见。其症状常被正常妊娠相关症状所掩盖,导致诊断延迟。基于我们对5例患者的经验及文献回顾,我们制定了一种治疗方案,该方案对肿瘤切除采取积极方法,但尽可能维持妊娠及生育能力。大多数患者预后较差,因为肿瘤在诊断时通常已处于晚期。与所有癌症一样,提高生存率的关键在于早期诊断和治疗。