The Impact of on Oral and Systemic Health: A Comprehensive Review of Recent Research.

Oral diseases, particularly dental caries and periodontal disease, pose significant global health challenges. The imbalance of the oral microbiota plays a key role in the occurrence of these diseases, prompting researchers to seek new strategies to restore oral ecological balance. is a Gram-positive rod-shaped bacterium that exists in various body parts of humans, including the gastrointestinal tract, urinary tract, skin, and so on. This species has a potentially positive impact on oral health and plays an important role in maintaining systemic health. Recent studies have explored the application of in the prevention and treatment of oral diseases, and its impact on systemic health has also been preliminarily revealed. The current review summarizes the role of in oral health and systemic health and outlines its potential applications in the future. has shown promising prospects in treating non-communicable biofilm-dependent oral diseases, but its mechanism of action and efficacy still need further research. In addition, has also displayed some potential benefits in promoting overall health. Future research should focus on revealing the specific pathways of action of , screening for the most beneficial strains, determining the most effective drug delivery strategies, developing oral and systemic health products based on , and ensuring their safety in clinical applications.