Dellinger J A, Taylor H L
Aviat Space Environ Med. 1985 Mar;56(3):254-7.
The Aviation Research Laboratory has developed a methodology for evaluating toxicant effects on pilot performance. Flight data are collected using a digital flight simulator, the ILLIMAC (ILLInois Micro Aviation Computer), during holding patterns and instrument landing system approaches. The flight data are recorded by a separate microcomputer, which also presents the Sternberg memory searching task. A preliminary study examined pilot performance in the simulator and cholinesterase inhibition by insecticides in agricultural pilots. The correlation between the physiological parameters and the pilot performance data was determined. Experiments are planned to determine the effects of a variety of drugs on pilot performance. Neurotoxicants to be studied include ethanol, three antiemetic drugs, and atropine sulfate.
航空研究实验室已开发出一种评估毒物对飞行员表现影响的方法。在等待航线和仪表着陆系统进近过程中，使用数字飞行模拟器ILLIMAC（伊利诺伊微型航空计算机）收集飞行数据。飞行数据由一台单独的微型计算机记录，该微型计算机还呈现斯特恩伯格记忆搜索任务。一项初步研究考察了农业飞行员在模拟器中的表现以及杀虫剂对其胆碱酯酶的抑制作用。确定了生理参数与飞行员表现数据之间的相关性。计划开展实验以确定各种药物对飞行员表现的影响。拟研究的神经毒物包括乙醇、三种止吐药和硫酸阿托品。
