Vitiello Livio, De Bernardo Maddalena, De Pascale Ilaria, Salerno Giulio, Pellegrino Alfonso, Rosa Nicola
Eye Unit, "Luigi Curto" Hospital, Azienda Sanitaria Locale Salerno, 84035 Polla, SA, Italy.
Eye Unit, Department of Medicine, Surgery, and Dentistry "Scuola Medica Salernitana", University of Salerno, 84081 Baronissi, SA, Italy.
Life (Basel). 2024 Dec 30;15(1):31. doi: 10.3390/life15010031.
The abnormal growth of irregular new blood vessels into the subretinal or intraretinal space is known as macular neovascularization (MNV). People over 50 are often affected by this disorder, which is typically brought on by age-related macular degeneration. In addition, MNV can be found in people under 50 years of age, who may present primary ophthalmic diseases such as pathological myopia, angioid streaks, traumatic choroidal rupture, or suspected ocular histoplasmosis syndrome. However, it is important to consider a specific set of young individuals who may develop MNV even in the absence of pathological myopia or other identifiable inflammatory, peripapillary, post-traumatic, or degenerative fundus abnormalities. This latter condition is classified as idiopathic MNV. After a literature review focused on young patients affected by one of these two clinical entities, we report the case of a Caucasian young woman suffering for four years from an idiopathic and quiescent MNV that started exuding after childbirth, probably due to the induction with oxytocin, and was treated with intravitreal Aflibercept 2 mg injections.
不规则的新生血管异常生长进入视网膜下或视网膜内间隙被称为黄斑新生血管形成（MNV）。50岁以上的人常受这种疾病影响，它通常由年龄相关性黄斑变性引起。此外，MNV也可在50岁以下人群中发现，这些人可能患有原发性眼科疾病，如病理性近视、血管样条纹、外伤性脉络膜破裂或疑似眼组织胞浆菌病综合征。然而，有一组特定的年轻人即使在没有病理性近视或其他可识别的炎症、视乳头周围、创伤后或退行性眼底异常的情况下也可能发生MNV，这一点很重要。后一种情况被归类为特发性MNV。在对受这两种临床病症之一影响的年轻患者进行文献综述后，我们报告了一名白种年轻女性的病例，她患有特发性静止性MNV四年，产后开始渗出，可能是由于催产素的诱导，并接受了玻璃体内注射2mg阿柏西普治疗。
