Özkan Esra, Albayrak Tuna
Nursing Department, Faculty of Health Sciences, Surgical Diseases Nursing, Giresun Üniversitesi, Giresun, Türkiye.
Medical Faculty, Department of Anesthesia and Reanimation, Giresun Üniversitesi, Giresun, Türkiye.
J Perianesth Nurs. 2025 Aug;40(4):938-944. doi: 10.1016/j.jopan.2024.10.010. Epub 2025 Jan 23.
The aim in the present study was to evaluate the effects of chewing postoperative xylitol gum on gastrointestinal functional recovery after laparoscopic cholecystectomy.
A three-arm randomized controlled trial.
After a baseline assessment, participants were randomly assigned in three groups. The random assignment was performed by using a computer program (Microsoft Excel 2016). Afterward, participants were categorized into three subgroups. Group 3 was the control group that consisted of participants who had no intervention for chewing gum (n = 25). Group 2 was xylitol-free gum chewing group (n = 25), whereas Group 1 was xylitol gum chewing group (n = 24). In later phases, the time to first postsurgical flatus, time to first bowel sound after surgery, time to first postsurgical defecation, time to first mobilization after surgery, and discharge time from hospital were recorded. Nausea and vomiting, which are among the postoperative symptoms, were also evaluated.
The duration of the control group from the end of surgery to the flatulence and bowel sounds was statistically higher than the xylitol group and xylitol-free group (all P < .05). Also, first postoperative flatulence time of xylitol-free group was higher than the xylitol group (P < .05). The duration from the end of surgery to defecation was longer in the control group compared with the xylitol group and the xylitol-free group, with a statistically significant difference between the groups (P < .05). In this study, a statistically significant difference was observed in terms of the time to first postsurgical flatus, time to first bowel sound after surgery, and time to first postsurgical defecation (all P < .000). No significant difference was found between the xylitol group, xylitol-free group, and control group when discharge from hospital and mobilization times were analyzed (all of them are P > .05).
Chewing xylitol gum facilitates postoperative gastrointestinal recovery after laparoscopic cholecystectomy. Further studies are recommended to confirm these findings and investigate the underlying mechanisms.
本研究旨在评估咀嚼术后木糖醇口香糖对腹腔镜胆囊切除术后胃肠道功能恢复的影响。
一项三臂随机对照试验。
在进行基线评估后，参与者被随机分为三组。随机分组使用计算机程序（Microsoft Excel 2016）完成。之后，参与者被分为三个亚组。第3组为对照组，由未接受口香糖咀嚼干预的参与者组成（n = 25）。第2组为无糖口香糖咀嚼组（n = 25），而第1组为木糖醇口香糖咀嚼组（n = 24）。在后续阶段，记录首次术后排气时间、术后首次肠鸣音时间、首次术后排便时间、术后首次活动时间以及出院时间。还对术后症状中的恶心和呕吐进行了评估。
对照组从手术结束到出现肠胃胀气和肠鸣音的持续时间在统计学上高于木糖醇组和无糖组（所有P < 0.05）。此外，无糖组的首次术后排气时间高于木糖醇组（P < 0.05）。与木糖醇组和无糖组相比，对照组从手术结束到排便的持续时间更长，组间差异具有统计学意义（P < 0.05）。在本研究中，首次术后排气时间、术后首次肠鸣音时间和首次术后排便时间方面观察到统计学上的显著差异（所有P < 0.000）。分析出院和活动时间时，木糖醇组、无糖组和对照组之间未发现显著差异（所有P > 0.05）。
咀嚼木糖醇口香糖有助于腹腔镜胆囊切除术后胃肠道的恢复。建议进一步研究以证实这些发现并探究其潜在机制。
