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胰腺原发性鳞状细胞癌：一例报告。

Primary squamous cell carcinoma of the pancreas: A case report.

作者信息

Du Wei, Shi Rongyu, Shao Chunlong, Zhang Ning

机构信息

Department of Hepatopancreatobiliary Surgery, First People's Hospital of Jiashan County, Jiaxing, Zhejiang Province, China.

Department of Hepatopancreatobiliary Surgery, First People's Hospital of Jiashan County, Jiaxing, Zhejiang Province, China.

出版信息

Int J Surg Case Rep. 2025 Feb;127:110962. doi: 10.1016/j.ijscr.2025.110962. Epub 2025 Jan 25.

DOI:10.1016/j.ijscr.2025.110962
PMID:39870002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11795834/
Abstract

INTRODUCTION

Primary squamous cell carcinoma (SCC) is a rare type of pancreatic cancer with an extremely low incidence rate and a prognosis that is poorer than that of pancreatic ductal adenocarcinoma.

PRESENTATION OF CASE

We report a case of pure pancreatic SCC in an 80-year-old man. Based on the examination before surgical resection, we did not detect any SCC lesions that might have metastasized to the pancreas. Partial gastrectomy with caudal pancreatectomy and splenectomy were performed to remove the tumor. Histopathological examination of the resected specimen confirmed the diagnosis of poorly differentiated SCC of the pancreas with stomach invasion and regional lymph node metastasis. The patient was administered adjuvant chemotherapy.

DISCUSSION

SCC poses a diagnostic challenge, requiring histopathology for definitive diagnosis. As an aggressive disease with poor response to chemotherapy and radiotherapy, the prognosis for primary SCC is poor.

CONCLUSION

Surgical resection and ultrasound-guided fine needle aspiration (EUS-FNA) is helpful for obtaining samples for histopathology and cytology, thus improving diagnostic accuracy.

摘要

引言

原发性鳞状细胞癌（SCC）是一种罕见的胰腺癌类型，发病率极低，预后比胰腺导管腺癌更差。

病例介绍

我们报告一例80岁男性的纯胰腺SCC病例。在手术切除前的检查中，我们未发现任何可能已转移至胰腺的SCC病变。实施了部分胃切除术、胰尾切除术和脾切除术以切除肿瘤。对切除标本的组织病理学检查证实为胰腺低分化SCC伴胃侵犯和区域淋巴结转移。该患者接受了辅助化疗。

讨论

SCC带来诊断挑战，明确诊断需要组织病理学检查。作为一种对化疗和放疗反应不佳的侵袭性疾病，原发性SCC的预后较差。

结论

手术切除和超声引导下细针穿刺抽吸（EUS-FNA）有助于获取组织病理学和细胞学样本，从而提高诊断准确性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/119e23f1d9af/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/8aa189e8bacf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/e9678a67509c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/cd060b87b217/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/bd8a4fece8cc/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/71f500ef190a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/119e23f1d9af/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/8aa189e8bacf/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/e9678a67509c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/cd060b87b217/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/bd8a4fece8cc/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/71f500ef190a/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/443c/11795834/119e23f1d9af/gr6.jpg

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本文引用的文献

1
Cancer incidence and mortality in China, 2022.2022年中国癌症发病率与死亡率
J Natl Cancer Cent. 2024 Feb 2;4(1):47-53. doi: 10.1016/j.jncc.2024.01.006. eCollection 2024 Mar.
2
Primary squamous cell carcinoma of the pancreas: an update on a rare neoplasm from the SEER database.胰腺原发性鳞状细胞癌：来自监测、流行病学和最终结果（SEER）数据库的一种罕见肿瘤的最新情况
Front Oncol. 2023 Dec 7;13:1272740. doi: 10.3389/fonc.2023.1272740. eCollection 2023.
3
Case Report: A complete pathologic response in pancreatic cancer with squamous cell differentiation.
病例报告：胰腺具有鳞状细胞分化的癌出现完全病理缓解。
Front Oncol. 2023 Nov 29;13:1240405. doi: 10.3389/fonc.2023.1240405. eCollection 2023.
4
Primary squamous cell carcinoma of pancreas in a patient with chronic pancreatitis: A rare case report.一名慢性胰腺炎患者发生胰腺原发性鳞状细胞癌：一例罕见病例报告。
Radiol Case Rep. 2023 Mar 24;18(5):2024-2029. doi: 10.1016/j.radcr.2023.02.038. eCollection 2023 May.
5
The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南：更新共识外科病例报告（SCARE）指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
6
Primary Squamous Cell Carcinoma, a Rare Pathological Report of Pancreatic Cancer.原发性鳞状细胞癌，一份罕见的胰腺癌病理报告。
Caspian J Intern Med. 2021;12(Suppl 2):S407-S412. doi: 10.22088/cjim.12.0.407.
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Clin Gastroenterol Hepatol. 2021 May;19(5):876-884. doi: 10.1016/j.cgh.2020.02.054. Epub 2020 Mar 6.
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