Soni Jayesh, Pathak Nikhilesh, Gharia Mihir, Aswal Devina, Parikh Jaymin, Sharma Prachi, Mishra Astha, Lalan Dhvni, Maheshwari Twinkle
Department of Gastroenterology, Digestive Disease Clinic, Mumbai 400092, Mahārāshtra, India.
Department of Endocrinology, DPC Health and Diabetic Clinic, Delhi 110008, India.
World J Hepatol. 2025 Jan 27;17(1):101630. doi: 10.4254/wjh.v17.i1.101630.
Non-alcoholic fatty liver disease (NAFLD) management requires sustainable lifestyle modifications. This study aimed to evaluate the effectiveness of the RESET care plan, a comprehensive program that is an integrated personalized diet, exercise, and cognitive behavior therapy, delivered MyTatva's digital health application enabled through a body composition analyzer (BCA) and smartwatch.
To evaluates the effectiveness of the comprehensive program delivered MyTatva's digital health app enabled through internet of thing devices.
This retrospective observational study analyzed deidentified data from 22 participants enrolled in the MyTatva RESET care program. Participants were divided into three groups: Group A, diet plan; Group B, diet + exercise plan; and Group C, diet + exercise + cognitive behavioral therapy plan. Participants were provided with a BCA and smartwatch for continuous monitoring of anthropometric parameters. Statistical analysis, including one-way ANOVA and post-hoc Tukey's Honest Significant Difference test, was conducted to compare mean changes in anthropometric parameters across the groups.
All intervention groups showed significant improvement across all anthropometric parameters. Group C showed the most significant improvements, with mean weight reduction of 7% or more (6.99 ± 2.98 kg, 7.00% ± 3.39%; = 0.002) from baseline, a benchmark associated with improved NAFLD conditions. Post-hoc analysis revealed that Group C had significantly greater improvements than Groups A and B. Weight reduction was observed in 85.7% of Group A participants, 77.8% of Group B participants, and 100% of Group C participants.
The comprehensive RESET care plan achieved a 7% weight reduction in 12 weeks, demonstrating its effectiveness in managing NAFLD. These results support adopting digitally supported, patient-centric approaches for NAFLD treatment.
非酒精性脂肪性肝病（NAFLD）的管理需要可持续的生活方式改变。本研究旨在评估RESET护理计划的有效性，这是一个综合项目，通过身体成分分析仪（BCA）和智能手表启用的MyTatva数字健康应用程序提供综合个性化饮食、运动和认知行为疗法。
评估通过物联网设备启用的MyTatva数字健康应用程序提供的综合项目的有效性。
这项回顾性观察研究分析了22名参加MyTatva RESET护理项目的参与者的匿名数据。参与者被分为三组：A组，饮食计划；B组，饮食+运动计划；C组，饮食+运动+认知行为疗法计划。为参与者提供了BCA和智能手表，以持续监测人体测量参数。进行了包括单因素方差分析和事后Tukey诚实显著差异检验在内的统计分析，以比较各组人体测量参数的平均变化。
所有干预组在所有人体测量参数上均显示出显著改善。C组改善最为显著，与基线相比平均体重减轻7%或更多（6.99±2.98千克，7.00%±3.39%；P = 0.002），这一基准与改善的NAFLD状况相关。事后分析显示，C组的改善明显大于A组和B组。A组85.7%的参与者、B组77.8%的参与者和C组100%的参与者体重减轻。
全面的RESET护理计划在12周内实现了7%的体重减轻，证明了其在管理NAFLD方面的有效性。这些结果支持采用数字支持的、以患者为中心的方法治疗NAFLD。
