Luo Chengwen, Luo Zhilin
Department of Thoracic Surgery, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Front Oncol. 2025 Jan 13;14:1496265. doi: 10.3389/fonc.2024.1496265. eCollection 2024.
We report a rare case of locally advanced esophageal cancer with a right aortic arch (RAA), successfully treated with neoadjuvant immunotherapy and minimally invasive esophagectomy, guided by three-dimensional (3D) reconstruction.
A 50-year-old male with stage III esophageal squamous cell carcinoma (cT3N0M0) and RAA underwent four cycles of neoadjuvant immunotherapy with sintilimab, resulting in significant tumor regression. Minimally invasive esophagectomy was performed with the aid of preoperative 3D reconstruction, which was critical in navigating the complex vascular anatomy and ensuring surgical precision.
This case demonstrates the efficacy of neoadjuvant immunotherapy combined with 3D reconstruction in managing esophageal cancer complicated by vascular anomalies. This approach offers a promising alternative for complex cases where conventional treatments pose higher risks.
我们报告一例罕见的局部晚期食管癌合并右位主动脉弓（RAA）病例，该病例通过新辅助免疫治疗及在三维（3D）重建引导下的微创食管切除术成功治愈。
一名50岁男性，患有III期食管鳞状细胞癌（cT3N0M0）及RAA，接受了四个周期的信迪利单抗新辅助免疫治疗，肿瘤显著退缩。在术前3D重建的辅助下进行了微创食管切除术，这对于处理复杂的血管解剖结构及确保手术精准性至关重要。
本病例证明了新辅助免疫治疗联合3D重建在治疗合并血管异常的食管癌中的有效性。这种方法为传统治疗风险较高的复杂病例提供了一种有前景的替代方案。
