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药物性心房颤动的罕见表现：一例报告。

Unusual presentation of medication-induced atrial fibrillation: A case report.

作者信息

Hashim Thamir, Yigit Yavuz, Fadul Khalid Yasir, Dayraki Mostafa, Elmalik Ashraf, Alkahlout Baha Hamdi, Mohammad Aftab

机构信息

Department of Emergency Medicine Hamad Medical Corporation Doha Qatar.

Blizard Institute Queen Mary University London United Kingdom.

出版信息

Clin Case Rep. 2025 Jan 26;13(2):e9204. doi: 10.1002/ccr3.9204. eCollection 2025 Feb.

DOI:10.1002/ccr3.9204
PMID:39872704
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11769961/
Abstract

This case highlights that atrial fibrillation can occur as an adverse effect of tamsulosin even in younger patients at lower doses, challenging the conventional understanding that this complication primarily affects older individuals on higher doses. Clinicians should remain vigilant for this potential side effect across all patient demographics to ensure prompt identification and management.

摘要

该病例表明，即使在年轻患者中低剂量使用坦索罗辛时，也可能发生心房颤动这种不良反应，这对传统观念提出了挑战，即这种并发症主要影响高剂量用药的老年个体。临床医生应对所有患者群体中的这种潜在副作用保持警惕，以确保及时识别和处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/11769961/b7883188dca0/CCR3-13-e9204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/11769961/7807759e32d1/CCR3-13-e9204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/11769961/b7883188dca0/CCR3-13-e9204-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/11769961/7807759e32d1/CCR3-13-e9204-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/288b/11769961/b7883188dca0/CCR3-13-e9204-g001.jpg

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1
Unusual presentation of medication-induced atrial fibrillation: A case report.药物性心房颤动的罕见表现：一例报告。
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2
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本文引用的文献

1
Burden of atrial fibrillation and its attributable risk factors from 1990 to 2019: An analysis of the Global Burden of Disease study 2019.1990年至2019年心房颤动的负担及其可归因风险因素：对《2019年全球疾病负担研究》的分析
Front Cardiovasc Med. 2022 Oct 26;9:997698. doi: 10.3389/fcvm.2022.997698. eCollection 2022.
2
Global, regional, and national burden of disease study of atrial fibrillation/flutter, 1990-2019: results from a global burden of disease study, 2019.全球、区域和国家房颤/房扑疾病负担研究：2019 年全球疾病负担研究结果。
BMC Public Health. 2022 Nov 3;22(1):2015. doi: 10.1186/s12889-022-14403-2.
3
Tamsulosin-Induced Atrial Fibrillation With Rapid Ventricular Response.
坦索罗辛诱发的心房颤动伴快速心室反应。
Cureus. 2022 Jun 7;14(6):e25714. doi: 10.7759/cureus.25714. eCollection 2022 Jun.
4
Drug-Induced Arrhythmias: A Scientific Statement From the American Heart Association.药物性心律失常：美国心脏协会的科学声明。
Circulation. 2020 Oct 13;142(15):e214-e233. doi: 10.1161/CIR.0000000000000905. Epub 2020 Sep 15.
5
Initial Precipitants and Recurrence of Atrial Fibrillation.初始诱发因素与心房颤动的复发。
Circ Arrhythm Electrophysiol. 2020 Mar;13(3):e007716. doi: 10.1161/CIRCEP.119.007716. Epub 2020 Feb 12.
6
Mortality and causes of death in patients with atrial fibrillation: A nationwide population-based study.心房颤动患者的死亡率和死因：一项全国范围内基于人群的研究。
PLoS One. 2018 Dec 26;13(12):e0209687. doi: 10.1371/journal.pone.0209687. eCollection 2018.
7
Causes of autonomic dysfunction in idiopathic recurrent kidney stone formers.特发性复发性肾结石形成者自主神经功能障碍的原因。
Int Urol Nephrol. 2012 Jun;44(3):873-82. doi: 10.1007/s11255-011-9983-0. Epub 2011 May 11.
8
A 6-month large-scale study into the safety of tamsulosin.一项为期6个月的坦索罗辛安全性大规模研究。
Br J Clin Pharmacol. 2001 Jun;51(6):609-14. doi: 10.1046/j.0306-5251.2001.01388.x.
9
Doxazosin in benign prostatic hyperplasia: effects on blood pressure and urinary flow in normotensive and hypertensive men.多沙唑嗪治疗良性前列腺增生：对血压正常和高血压男性的血压及尿流的影响
Urology. 1995 Aug;46(2):182-6. doi: 10.1016/s0090-4295(99)80191-5.