Pingeton Blaire C, Evohr Bryn, Goodman Sherryl H
Institute for Innovations in Developmental Science, Department of Medical and Social Sciences, Northwestern University, 625 N Michigan Ave, Floor 24, Chicago, 60611, IL, USA.
Center for Community Health, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
Arch Womens Ment Health. 2025 Jan 28. doi: 10.1007/s00737-025-01558-1.
Pregnant and postpartum mothers with physical disabilities face discrimination in healthcare settings and high rates of maternal and obstetric complications, as well as having higher rates of lifetime depression prior to pregnancy, potentially increasing their likelihood of experiencing postpartum depression (PPD). Some studies have found higher rates of PPD in mothers with physical disabilities than in mothers without physical disabilities, with more disabling symptoms associated with worse PPD systems; however, the literature is sparse and heterogenous. This systematic review and meta-analysis advanced this area of study by evaluating the strength of the association between PPD and physical disability.
We searched PubMed and PsycInfo, with the primary inclusion criteria being that the studies had an established measure of depression in women during the postpartum period and either a cohort identified as having physical disability or an established measure of physical disability in a general population sample. We aggregated the prevalence of PPD in women with physical disabilities and tested the robustness of our findings to moderators, including region, sample population, and measure type.
Findings from our quantitative meta-analysis (n=14) demonstrated a strong (d=.76, p<.0001) association between PPD and physical disabilities, such that individuals with physical disabilities reported more depression symptoms than individuals without physical disabilities. Moderator analyses were null, revealing that the association between PPD and physical disabilities was robust to several variables. Qualitative results support our conclusion that individuals with physical disabilities are at increased risk of PPD symptoms.
Our findings of a strong association between physical disability and PPD support the need for more research. Additional studies would 1) augment a nuanced understanding of how best to conceptualize PPD in women with physical disabilities and 2) facilitate testing the robustness of the association between PPD and physical disabilities to additional important moderators.
身体残疾的孕妇和产后母亲在医疗保健环境中面临歧视,孕产妇和产科并发症发生率较高,且孕前终生抑郁发生率也较高,这可能增加她们患产后抑郁症(PPD)的可能性。一些研究发现,身体残疾母亲的产后抑郁症发生率高于无身体残疾的母亲,残疾症状越严重,产后抑郁症症状越差;然而,相关文献稀少且参差不齐。本系统评价和荟萃分析通过评估产后抑郁症与身体残疾之间关联的强度,推进了该研究领域的发展。
我们检索了PubMed和PsycInfo,主要纳入标准为:研究中有产后女性抑郁的既定测量方法,以及在队列研究中确定为有身体残疾的人群,或在一般人群样本中有身体残疾的既定测量方法。我们汇总了身体残疾女性产后抑郁症的患病率,并测试了研究结果对包括地区、样本人群和测量类型等调节因素的稳健性。
我们的定量荟萃分析(n = 14)结果表明,产后抑郁症与身体残疾之间存在强烈关联(d = 0.76,p <.0001),即身体残疾的个体比无身体残疾的个体报告更多的抑郁症状。调节因素分析结果无统计学意义,表明产后抑郁症与身体残疾之间的关联对多个变量具有稳健性。定性结果支持我们的结论,即身体残疾个体出现产后抑郁症症状的风险增加。
我们关于身体残疾与产后抑郁症之间存在强烈关联的研究结果支持开展更多研究的必要性。更多研究将:1)加深对如何最好地将身体残疾女性的产后抑郁症概念化的细微理解;2)有助于测试产后抑郁症与身体残疾之间的关联对其他重要调节因素的稳健性。