Experimental Medicine Program, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
International Collaboration on Repair Discoveries, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
J Spinal Cord Med. 2021 Mar;44(2):247-252. doi: 10.1080/10790268.2019.1666239. Epub 2019 Sep 24.
To examine the prevalence of postpartum depression (PPD) and postpartum anxiety (PPA) in mothers with spinal cord injury (SCI). Retrospective, cross-sectional study. Online multi-national study. We surveyed an international sample of 102 women who gave birth following cervical SCI (C1-C8, = 30), upper thoracic SCI (T1-T6, = 12) or lower level SCI (T7 & below, = 60). Participants were primarily from Canada and Sweden, and mean age at childbirth was 30 ± 6 years. Subscales from the Pregnancy Risk Assessment Monitoring System (PRAMS) were used to measure PPD (PRAMS-3D) and PPA (PRAMS-2A). PPD and PPA were most prevalent in women with cervical SCI, followed by upper thoracic SCI then lower SCI. Self-reported PPD was more prevalent than clinically diagnosed PPD in women with cervical SCI ( = 0.03) and upper thoracic SCI ( = 0.03). With cervical SCI, 75% of women diagnosed with MDD before pregnancy scored >9 on the PRAMS PPD subscale, indicating clinically relevant PPD. However, only 10% were diagnosed with PPD. Of women with lower SCI diagnosed with MDD before pregnancy, 25% had a clinically relevant score for self-reported PPD; 7% were diagnosed. This is currently the largest study examining PPD and PPA after SCI. Clinicians should be aware that mothers with SCI (particularly high-level SCI) may have increased risk of PPD and PPA. PPD is poorly understood in women with SCI and may even be underdiagnosed. SCI-related risk factors for PPD and PPA should be explored.
调查脊髓损伤(SCI)后产妇产后抑郁(PPD)和产后焦虑(PPA)的发生率。
回顾性、横断面研究。多国在线研究。我们调查了 102 名颈髓损伤(C1-C8,n=30)、胸髓损伤(T1-T6,n=12)或低水平 SCI(T7 及以下,n=60)后分娩的母亲的国际样本。参与者主要来自加拿大和瑞典,分娩时的平均年龄为 30±6 岁。使用妊娠风险评估监测系统(PRAMS)的子量表来衡量 PPD(PRAMS-3D)和 PPA(PRAMS-2A)。
颈髓损伤女性 PPD 和 PPA 发生率最高,其次是胸髓损伤,然后是低水平 SCI。颈髓损伤和胸髓损伤女性自我报告的 PPD 发生率高于临床诊断的 PPD(颈髓损伤: = 0.03;胸髓损伤: = 0.03)。在颈髓损伤中,75%的产前被诊断为 MDD 的女性在 PRAMS PPD 子量表上的评分>9,表明存在临床相关的 PPD。然而,只有 10%被诊断为 PPD。在产前被诊断为 MDD 的低水平 SCI 女性中,25%的人自我报告的 PPD 具有临床相关性评分;7%被诊断。这是目前研究 SCI 后 PPD 和 PPA 的最大规模研究。
临床医生应意识到,SCI 母亲(尤其是高水平 SCI 母亲)可能有更高的 PPD 和 PPA 风险。SCI 女性的 PPD 认识不足,甚至可能被低估。应探讨与 SCI 相关的 PPD 和 PPA 的风险因素。