Mathenjwa Thulile, Malila Bessie, Knight Lucia, Tanser Frank, Makwambeni Patricia, Phillips Tamsin K
Africa Health Research Institute, Krith building level 3, 719 Umbilo rd, Durban, 4001, South Africa.
Division of Epidemiology & Biostatistics, School of Public Health, University of Cape Town, Cape Town, South Africa.
Syst Rev. 2025 Jan 28;14(1):28. doi: 10.1186/s13643-024-02747-2.
Human mobility is associated with an increased risk of HIV acquisition and disengagement from HIV care, leading to poorer health outcomes among highly mobile individuals compared to less mobile individuals. Mobile individuals, broadly defined as those who temporally, seasonally, or permanently move from one place to another for voluntary or involuntary reasons, face many challenges in accessing HIV care services. These challenges include logistical difficulties, interruptions in HIV care continuity, and limited access to services across different locations, which together hinder timely testing, treatment initiation, and viral suppression. Digital health interventions offer flexible approaches that can adjust to the mobile individual's location to improve HIV care engagement and health outcomes for this underserved and hard-to-reach population. However, evidence on the feasibility, acceptability, and efficacy of digital health interventions across the HIV care cascade among mobile populations has not yet been appraised.
We seek to synthesize empirical evidence on the feasibility, acceptability, and efficacy of digital health interventions targeting the HIV care cascade among mobile populations.
We will conduct a mixed methods systematic review of peer reviewed studies published between 1 January 2010 and 31 July 2024 that evaluated digital health interventions targeting the HIV care cascade among mobile populations. We will search PubMed, Web of Science, and EBSCOhost (Academic Search Premier, Africa-Wide information, CINAHL, Health Source: Nursing/Academic Edition, APA PsycInfo, APA PsycArticles) electronic databases. Bibliographies of retrieved studies will also be reviewed for relevant citations. Only studies published in English language and involved a digital health intervention, report an outcome related to the HIV care cascade, and involve mobile populations either partially or completely will be included. Two reviewers will independently screen titles and abstracts against the inclusion criteria, followed by full text screening for eligible articles. In case of disagreements, consensus will be sought from a third reviewer. Data synthesis will follow the Joanne Briggs Institute's convergent segregated approach. If sufficient quantitative studies with comparable outcome measures are available, a meta-analysis will be performed.
This review will address a critical evidence gap by consolidating data on digital health interventions' feasibility, acceptability, and efficacy across the HIV care cascade among mobile populations. The results will inform the development of tailored digital health interventions to enhance HIV care delivery and health outcomes for this hard-to-reach population, supporting global HIV prevention and treatment goals.
This protocol is registered on PROSPERO (CRD42024528122).
人员流动与感染艾滋病毒的风险增加以及脱离艾滋病毒护理相关，导致流动性高的个体相比流动性较低的个体健康结果更差。流动个体广义上指那些因自愿或非自愿原因在时间上、季节上或永久地从一个地方搬到另一个地方的人，他们在获得艾滋病毒护理服务方面面临许多挑战。这些挑战包括后勤困难、艾滋病毒护理连续性中断以及不同地点服务获取受限，这些因素共同阻碍了及时检测、开始治疗和病毒抑制。数字健康干预提供了灵活的方法，可以根据流动个体的位置进行调整，以改善这一服务不足且难以接触到的人群的艾滋病毒护理参与度和健康结果。然而，关于数字健康干预在流动人群艾滋病毒护理连续过程中的可行性、可接受性和有效性的证据尚未得到评估。
我们旨在综合关于针对流动人群艾滋病毒护理连续过程的数字健康干预的可行性、可接受性和有效性的实证证据。
我们将对2010年1月1日至2024年7月31日期间发表的同行评审研究进行混合方法系统评价，这些研究评估了针对流动人群艾滋病毒护理连续过程的数字健康干预。我们将检索PubMed、科学网和EBSCOhost（学术搜索高级版、非洲范围信息、护理学与健康领域数据库、健康资源：护理/学术版、美国心理学会心理学文摘数据库、美国心理学会心理学全文数据库）电子数据库。还将审查检索到的研究的参考文献以获取相关引用。仅纳入以英文发表、涉及数字健康干预、报告与艾滋病毒护理连续过程相关的结果且部分或完全涉及流动人群的研究。两名评审员将根据纳入标准独立筛选标题和摘要，随后对符合条件的文章进行全文筛选。如有分歧，将寻求第三位评审员的共识。数据综合将遵循乔安妮·布里格斯研究所的收敛性分离方法。如果有足够数量具有可比结果测量的定量研究，将进行荟萃分析。
本综述将通过整合关于数字健康干预在流动人群艾滋病毒护理连续过程中的可行性、可接受性和有效性的数据，填补关键的证据空白。研究结果将为制定量身定制的数字健康干预措施提供信息，以加强对这一难以接触到的人群的艾滋病毒护理服务提供和健康结果，支持全球艾滋病毒预防和治疗目标。
本方案已在PROSPERO（CRD42024528122）上注册。
