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巴西干眼症的患病率:家庭调查揭示城乡地区差异。

Prevalence of dry eye in Brazil: Home survey reveals differences in urban and rural regions.

作者信息

Pereira Leidiane Adriano, Arantes Laura Braga, Persona Etiene Lorriane de Souza, Garcia Denny Marcos, Persona Isvander Gustavo de Souza, Pontelli Regina Celia Nucci, Rocha Eduardo M

机构信息

Department of Ophthalmology, Otorhinolaryngology, and Head & Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

Department of Ophthalmology, Otorhinolaryngology, and Head & Neck Surgery, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.

出版信息

Clinics (Sao Paulo). 2025 Jan 28;80:100578. doi: 10.1016/j.clinsp.2025.100578. eCollection 2025.

DOI:10.1016/j.clinsp.2025.100578
PMID:39879905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11814509/
Abstract

PURPOSE

A random home visit search investigated the prevalence and predictors of Dry Eye (DE) symptoms in Brazil.

METHODS

Through home visits to 420 urban and 180 rural residences in the countryside of Southeast Brazil, the Dry Eye Disease Short Questionnaire (DEDSQ) was applied to volunteers 40 years and older. The predictive value of the DEDSQ and the risk factors were investigated.

RESULTS

DE is more frequent in the urban population (38.1 % vs. 20 %; p < 0.0001) and was higher in females (37.5 % and 21.5 %; p < 0.0001). In the urban area, DE is associated with dyslipidemia (p < 0.0001), visual display terminal use > 2 h/day (p < 0.0001), and pterygium (p < 0.001), and in the rural area with dyslipidemia (p < 0.01) and prior ocular surgery (p < 0.05). In women, the predictors are antiallergics, chronic pelvic pain, fibromyalgia, and visual display terminal use > 2h/day. Aging was associated with distinct risk factors. DEDSQ showed 78.5 % of sensitivity and 71.1 % specificity.

CONCLUSION

This first domiciliary study in Brazil reveals that DE symptoms were more prevalent in the urban area and among women. DE has distinct risk factors and a high prevalence in Brazil.

摘要

目的

一项随机家访调查研究了巴西干眼症(DE)症状的患病率及预测因素。

方法

通过对巴西东南部农村地区420户城市家庭和180户农村家庭进行家访,对40岁及以上的志愿者应用干眼症疾病简短问卷(DEDSQ)。研究了DEDSQ的预测价值及危险因素。

结果

干眼症在城市人群中更为常见(38.1%对20%;p<0.0001),女性患病率更高(37.5%和21.5%;p<0.0001)。在城市地区,干眼症与血脂异常(p<0.0001)、每天使用视觉显示终端>2小时(p<0.0001)和翼状胬肉(p<0.001)相关,在农村地区与血脂异常(p<0.01)和既往眼部手术(p<0.05)相关。在女性中,预测因素为抗过敏药、慢性盆腔疼痛、纤维肌痛和每天使用视觉显示终端>2小时。衰老与不同的危险因素相关。DEDSQ的敏感性为78.5%,特异性为71.1%。

结论

巴西的这项首次家庭研究表明,干眼症症状在城市地区和女性中更为普遍。干眼症在巴西有不同的危险因素且患病率较高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09db/11814509/63d521047de0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09db/11814509/63d521047de0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09db/11814509/63d521047de0/gr1.jpg

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Prevalence and associated risk factors for dry eye disease among Brazilian undergraduate students.巴西大学生干眼症的患病率及相关危险因素。
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