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经皮介入治疗股浅动脉后长期再狭窄风险评分系统的比较。

Comparison of the risk scoring systems in long term restenosis due to percutaneous interventions to the superficial femoral artery.

作者信息

Karakayalı Muammer, Artac Inanç, Ilis Doğan, Omar Timor, Arslan Ayca, Guzel Ezgi, Karabag Yavuz, Rencuzogullari Ibrahim

机构信息

Department of Cardiology, Kafkas University School of Medicine, Kars, Turkey.

出版信息

Vasa. 2025 May;54(3):184-191. doi: 10.1024/0301-1526/a001178. Epub 2025 Jan 30.

Abstract

Percutaneous superficial femoral interventions remain the preferred method of treatment for superficial femoral artery (SFA) disease. Nevertheless, long term restenosis continues to be a major limitation of percutaneous interventions. In this context, the objective of this study is to compare the efficacies of CHA2DS2-VASc, CHA2DS2-VASc-HS, ATRIA, ATRIA-HSV, and HATCH risk scoring systems in predicting long-term (5 years) restenosis due to percutaneous interventions to the superficial femoral artery. The sample of this retrospective study consisted of 545 peripheral artery disease (PAD) patients with a percutaneous intervention to the SFA. Of these patients, 362 and 183 were included in the group of PAD patients without long-term (5 years) SFA restenosis (Group 1) and in the group of PAD patients with long-term SFA restenosis (Group 2). The efficacies of CHA2DS2-VASc, CHA2DS2-VASc-HS, ATRIA, ATRIA-HSV, and HATCH risk scoring systems in predicting the development of long-term SFA restenosis were comparatively analyzed. CHA2DS2-VASc, CHA2DS2-VASc-HS, ATRIA, ATRIA-HSV, and HATCH risk scores all increased with long-term SFA restenosis. The receiver operating characteristic (ROC) curve analysis revealed that all five risk scoring systems successfully predicted long-term SFA restenosis, whereas the paired ROC curve analysis revealed that CHA2DS2-VASc-HS scores of >4 had the best prognostic power in predicting long term SFA restenosis. The study findings indicated that the CHA2DS2-VASc-HS score was an independent predictor of the development of SFA restenosis. The CHA2DS2-VASc-HS risk scoring system, which is the modified version of CHA2DS2-VASc, outperformed the CHA2DS2-VASc, HATCH, ATRIA, and ATRIA-HSV, the modified version of ATRIA, risk scoring systems in predicting long-term (5 years) SFA restenosis.

摘要

经皮股浅动脉介入治疗仍是股浅动脉(SFA)疾病的首选治疗方法。然而,长期再狭窄仍然是经皮介入治疗的主要限制因素。在此背景下,本研究的目的是比较CHA2DS2-VASc、CHA2DS2-VASc-HS、ATRIA、ATRIA-HSV和HATCH风险评分系统在预测经皮股浅动脉介入治疗导致的长期(5年)再狭窄方面的有效性。这项回顾性研究的样本包括545例接受SFA经皮介入治疗的外周动脉疾病(PAD)患者。其中,362例和183例分别纳入无长期(5年)SFA再狭窄的PAD患者组(第1组)和有长期SFA再狭窄的PAD患者组(第2组)。对CHA2DS2-VASc、CHA2DS2-VASc-HS、ATRIA、ATRIA-HSV和HATCH风险评分系统预测长期SFA再狭窄发生的有效性进行了比较分析。CHA2DS2-VASc、CHA2DS2-VASc-HS、ATRIA、ATRIA-HSV和HATCH风险评分均随长期SFA再狭窄而升高。受试者工作特征(ROC)曲线分析显示,所有五个风险评分系统均能成功预测长期SFA再狭窄,而配对ROC曲线分析显示,CHA2DS2-VASc-HS评分>4在预测长期SFA再狭窄方面具有最佳的预后能力。研究结果表明,CHA2DS2-VASc-HS评分是SFA再狭窄发生的独立预测因素。CHA2DS2-VASc-HS风险评分系统是CHA2DS2-VASc的改良版本,在预测长期(5年)SFA再狭窄方面优于CHA2DS2-VASc、HATCH、ATRIA以及ATRIA的改良版本ATRIA-HSV风险评分系统。

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