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糖尿病周围神经病变门诊患者的抑郁:患病率及相关因素

Depression among outpatients with diabetic peripheral neuropathy: prevalence and associated factors.

作者信息

Gharaibeh Besher, Baniyones Aya, Abuhammad Sawsan, Mehrass Amat Al-Khaleq O

机构信息

Department of Adult Health Nursing, Faculty of Nursing, Jordan University of Science and Technology, Irbid, Jordan.

Department of Nursing, College of Health Sciences, University of Sharjah, Sharjah, UAE.

出版信息

Future Sci OA. 2025 Dec;11(1):2458989. doi: 10.1080/20565623.2025.2458989. Epub 2025 Jan 31.

DOI:10.1080/20565623.2025.2458989
PMID:39887078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11792793/
Abstract

AIM

This study aims to assess the prevalence of depression among patients with diabetic neuropathy and identify contributing factors.

METHODS

A cross-sectional descriptive design was used, recruiting 153 patients from outpatient clinics. Participants completed the Beck Depression Inventory II, Michigan Neuropathy Screening Instrument, and Douleur Neuropathique 4 questionnaires, with recent A1C results obtained from medical records.

RESULTS

The mean depression score was 16.5, with 98 patients (65%) reporting depression and 20 (13%) indicating moderate to severe depression. Approximately half of the sample experienced neuropathy and neuropathic pain. The mean Michigan Neuropathy Screening Instrument score was 5 (SD = 5), and the Douleur Neuropathique 4 score was 4 (SD = 3.5). Regression analyses showed significant demographic influences on depression. Higher Michigan Neuropathy Screening scores predicted greater depression severity, while DN4 scores did not significantly impact depression levels.

CONCLUSIONS

Depression in patients with diabetic neuropathy is influenced by the severity of neuropathy. Factors commonly associated with depression in diabetes, such as pain intensity and glycemic control, do not significantly affect depression in the context of neuropathy. These findings highlight the complexity of addressing depression in diabetes care, requiring comprehensive and ongoing approaches.

摘要

目的

本研究旨在评估糖尿病神经病变患者中抑郁症的患病率,并确定相关影响因素。

方法

采用横断面描述性设计,从门诊招募了153名患者。参与者完成了贝克抑郁量表第二版、密歇根神经病变筛查量表和神经病理性疼痛4问卷,并从病历中获取了近期糖化血红蛋白(A1C)结果。

结果

抑郁平均得分为16.5,98名患者(65%)报告有抑郁,20名(13%)表明有中度至重度抑郁。约一半的样本有神经病变和神经性疼痛。密歇根神经病变筛查量表平均得分为5(标准差=5),神经病理性疼痛4问卷得分为4(标准差=3.5)。回归分析显示人口统计学因素对抑郁有显著影响。密歇根神经病变筛查量表得分越高,预测抑郁严重程度越高,而神经病理性疼痛4问卷得分对抑郁水平无显著影响。

结论

糖尿病神经病变患者的抑郁受神经病变严重程度影响。糖尿病中通常与抑郁相关的因素,如疼痛强度和血糖控制,在神经病变背景下对抑郁无显著影响。这些发现凸显了糖尿病护理中解决抑郁问题的复杂性,需要全面且持续的方法。

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Short- and long-term test-retest reliability of the English version of the 7-item DN4 questionnaire - a screening tool for neuropathic pain.7 项 DN4 问卷英文版的短期和长期重测信度 - 一种用于筛查神经性疼痛的工具。
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A systematic review and meta-analysis to compare the prevalence of depression between people with and without Type 1 and Type 2 diabetes.一项比较1型和2型糖尿病患者与非糖尿病患者抑郁症患病率的系统评价和荟萃分析。
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