Farooqi Aaisha, Gillies Clare, Sathanapally Harini, Abner Sophia, Seidu Sam, Davies Melanie J, Polonsky William H, Khunti Kamlesh
Department of Psychology, Birmingham City University, UK.
Leicester Real World Evidence Unit, University of Leicester, UK.
Prim Care Diabetes. 2022 Feb;16(1):1-10. doi: 10.1016/j.pcd.2021.11.001. Epub 2021 Nov 19.
Diabetes can significantly impact quality of life and mental health. However, inconsistencies have been reported in the prevalence of depression in those with Type 1 and Type 2 diabetes, and those without. Systematic reviews also included studies without adequate control subjects. We update existing literature, by comparing depression prevalence between individuals with and without Type 1 and Type 2 diabetes.
A systematic review and meta-analysis. We searched MEDLINE, EMBASE and PSYCHINFO, from January 1985 to August 2021. Studies were excluded if they failed to have an adequate control group, specified type of diabetes, or reported depression prevalence by type of diabetes.
44 studies were selected for inclusion. The prevalence of depression was significantly higher in people with Type 1 (22% vs 13%, OR = 2.10 (95% CI: 1.23, 3.52)), or Type 2 diabetes (19% vs 11%, OR = 1.76 (1.55, 2.01)) compared to those without diabetes. There was no association between study effect size and mean age or gender. Findings did not significantly differ between methods of depression assessment. Prevalence of depression in people with diabetes was higher in studies carried out in specialist care (36%, OR = 3.14 (2.12, 4.63)) compared to those in community or primary care (12%, OR = 1.51 (1.35, 1.70) and in low- and middle-income countries (OR = 2.58 (1.91, 3.50) compared to countries with high income economies (OR = 1.59 (1.39, 1.82)).
Depression prevalence remains significant in those with type 1 and type 2 diabetes. Effective chronic disease management in people with diabetes is important, particularly screening and managing depression and diabetes distress in specialist care settings.
糖尿病会显著影响生活质量和心理健康。然而，1型和2型糖尿病患者以及非糖尿病患者中抑郁症患病率的报道并不一致。系统评价还纳入了没有足够对照受试者的研究。我们通过比较1型和2型糖尿病患者与非糖尿病患者的抑郁症患病率来更新现有文献。
进行系统评价和荟萃分析。我们检索了1985年1月至2021年8月期间的MEDLINE、EMBASE和PSYCHINFO数据库。如果研究没有足够的对照组、未明确糖尿病类型或未按糖尿病类型报告抑郁症患病率，则将其排除。
共纳入44项研究。与非糖尿病患者相比，1型糖尿病患者（22% 对13%，OR = 2.10（95% CI：1.23，3.52））和2型糖尿病患者（19% 对11%，OR = 1.76（1.55，2.01））的抑郁症患病率显著更高。研究效应大小与平均年龄或性别之间没有关联。抑郁症评估方法之间的结果没有显著差异。与社区或初级保健环境中的研究（12%，OR = 1.51（1.35，1.70））相比，在专科护理环境中进行的研究中糖尿病患者的抑郁症患病率更高（36%，OR = 3.14（2.12，4.63）），与高收入经济体国家相比，低收入和中等收入国家的糖尿病患者抑郁症患病率更高（OR = 2.58（1.91，3.50））（OR = 1.59（1.39，1.82））。
1型和2型糖尿病患者的抑郁症患病率仍然很高。对糖尿病患者进行有效的慢性病管理很重要，特别是在专科护理环境中筛查和管理抑郁症及糖尿病困扰。
