• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

筛窦息肉患者上颌窦的临床病理变化:一项前瞻性观察研究。

Clinicopathological Changes of the Maxillary Sinus in Patients With Ethmoidal Polyposis: A Prospective Observational Study.

作者信息

Samal Dillip Kumar, Chirom Amit, Mallick Saumyaranjan, Gupta Vikas, Behera Ganakalyan

机构信息

Otorhinolaryngology, All India Institute of Medical Sciences, Bhubaneswar, Bhubaneswar, IND.

Otorhinolaryngology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.

出版信息

Cureus. 2025 Jan 1;17(1):e76730. doi: 10.7759/cureus.76730. eCollection 2025 Jan.

DOI:10.7759/cureus.76730
PMID:39897206
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11784411/
Abstract

OBJECTIVE OF STUDY

To determine the clinical, radiological and histopathological changes in maxillary antrum compared to ethmoid sinuses in patients with chronic sinusitis with nasal polyposis.

STUDY DESIGN

This is a prospective observational study conducted in a tertiary care hospital.

MATERIALS AND METHODS

A total number of 30 primary cases of inflammatory nasal polypi, not responding to conservative measures, were evaluated clinically and radiologically. They underwent endoscopic sinus surgery, and all sinuses were cleared of diseases. Histopathological evaluation of both maxillary sinus and ethmoid sinuses was done and compared.

RESULTS

Among 30 patients with 60 nasal cavities studied, nearly all showed partial or complete opacity of their maxillary antrum and blocked osteomeatal complexes on radiology. But, only a few patients (16.67%) showed frank polypi in their antrum intra-operatively. On histopathology, antral mucosa showed rare involvement, and the submucosa showed variable grades of inflammation, but it was significantly less compared to ethmoids.

CONCLUSION

Although maxillary antrum gets involved clinically in nearly all polyposis cases, pathological involvement is unlikely compared to ethmoid sinuses. Thus, it indicates a secondary inflammatory change in maxillary sinuses rather than primary involvement.

摘要

研究目的

确定慢性鼻窦炎伴鼻息肉患者上颌窦与筛窦相比的临床、放射学和组织病理学变化。

研究设计

这是一项在三级护理医院进行的前瞻性观察研究。

材料与方法

对30例对保守治疗无反应的原发性炎性鼻息肉患者进行临床和放射学评估。他们接受了鼻内镜鼻窦手术,所有鼻窦的疾病均被清除。对上颌窦和筛窦进行了组织病理学评估并进行比较。

结果

在研究的30例患者的60个鼻腔中,几乎所有患者的上颌窦在放射学上均显示部分或完全混浊,且骨窦复合体阻塞。但是,术中仅有少数患者(16.67%)的上颌窦出现明显息肉。组织病理学检查显示,上颌窦黏膜受累罕见,黏膜下层炎症程度各异,但与筛窦相比明显较轻。

结论

虽然几乎所有息肉病患者的上颌窦在临床上都会受累,但与筛窦相比,病理受累的可能性较小。因此,这表明上颌窦的炎症变化是继发性的,而非原发性受累。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/2bd4d8a01bdf/cureus-0017-00000076730-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/089c6005f95a/cureus-0017-00000076730-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/7bd57f14ef2b/cureus-0017-00000076730-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/32059c25ca16/cureus-0017-00000076730-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/2bd4d8a01bdf/cureus-0017-00000076730-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/089c6005f95a/cureus-0017-00000076730-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/7bd57f14ef2b/cureus-0017-00000076730-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/32059c25ca16/cureus-0017-00000076730-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/238c/11784411/2bd4d8a01bdf/cureus-0017-00000076730-i04.jpg

相似文献

1
Clinicopathological Changes of the Maxillary Sinus in Patients With Ethmoidal Polyposis: A Prospective Observational Study.筛窦息肉患者上颌窦的临床病理变化:一项前瞻性观察研究。
Cureus. 2025 Jan 1;17(1):e76730. doi: 10.7759/cureus.76730. eCollection 2025 Jan.
2
Unilateral pathological lesions of paranasal sinuses removed by endoscopic surgery.经鼻内镜手术切除的单侧鼻窦病理性病变。
Otolaryngol Pol. 2014 Mar-Apr;68(2):83-8. doi: 10.1016/j.otpol.2013.07.002. Epub 2013 Jul 5.
3
Comparison of inflammatory cell profile and Th2 cytokine expression in the ethmoid sinuses, maxillary sinuses, and turbinates of atopic subjects with chronic sinusitis.变应性慢性鼻窦炎患者筛窦、上颌窦及鼻甲中炎性细胞谱和Th2细胞因子表达的比较。
Otolaryngol Head Neck Surg. 1998 Jun;118(6):804-9. doi: 10.1016/S0194-5998(98)70273-6.
4
The microbiology of ethmoid and maxillary sinuses in patients with chronic sinusitis.慢性鼻窦炎患者筛窦和上颌窦的微生物学
Am J Otolaryngol. 2003 May-Jun;24(3):163-8. doi: 10.1016/s0196-0709(02)32420-7.
5
Preoperative CT scanning for endoscopic sinus surgery: a rational approach.用于鼻内镜鼻窦手术的术前CT扫描:一种合理的方法。
Clin Otolaryngol Allied Sci. 1992 Feb;17(1):60-6. doi: 10.1111/j.1365-2273.1992.tb00990.x.
6
Functional endoscopic sinus surgery. Concept, indications and results of the Messerklinger technique.功能性鼻内镜鼻窦手术。梅塞尔克林格技术的概念、适应证及结果。
Eur Arch Otorhinolaryngol. 1990;247(2):63-76. doi: 10.1007/BF00183169.
7
Computed Tomography in the Evaluation of Pathological Lesions of Paranasal Sinuses.计算机断层扫描在评估鼻窦病理病变中的应用
J Nepal Health Res Counc. 2015 May-Aug;13(30):116-20.
8
Frequency of the odontogenic maxillary sinusitis extended to the anterior ethmoid sinus and response to surgical treatment.牙源性上颌窦炎累及前组筛窦的频率及对手术治疗的反应。
Med Oral Patol Oral Cir Bucal. 2014 Jul 1;19(4):e409-13. doi: 10.4317/medoral.19629.
9
Supra Maxillary Cell (SMC): An Anatomical variant of Ethmoid Sinus.上颌窦上房(SMC):筛窦的一种解剖变异。
Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):870-874. doi: 10.1007/s12070-020-01947-1. Epub 2020 Jul 7.
10
Assessing volume growth of paranasal sinuses and nasal cavity in children using three-dimensional imaging software.使用三维成像软件评估儿童鼻窦和鼻腔的容积增长情况。
Auris Nasus Larynx. 2024 Dec;51(6):917-921. doi: 10.1016/j.anl.2024.08.007. Epub 2024 Sep 13.

本文引用的文献

1
Nasal polyposis: an overview of differential diagnosis and treatment.鼻息肉病:鉴别诊断与治疗概述
Recent Pat Inflamm Allergy Drug Discov. 2011 Sep;5(3):241-52. doi: 10.2174/187221311797264900.
2
Histopathologic characteristics of inferior turbinate vs ethmoidal polypin chronic rhinosinusitis.下鼻甲与筛窦息肉在慢性鼻-鼻窦炎中的组织病理学特征。
Ann Diagn Pathol. 2011 Aug;15(4):233-6. doi: 10.1016/j.anndiagpath.2010.10.009. Epub 2011 Mar 10.
3
Is routine histopathological analysis of nasal polyposis specimens necessary?
是否有必要对鼻息肉标本进行常规组织病理学分析?
Eur Arch Otorhinolaryngol. 2011 Jul;268(7):1013-5. doi: 10.1007/s00405-011-1534-x. Epub 2011 Feb 18.
4
Outcomes after endoscopic sinus surgery for unilateral versus bilateral chronic rhinosinusitis with nasal polyposis.单侧与双侧慢性鼻-鼻窦炎伴鼻息肉患者行内镜鼻窦手术的疗效比较。
Am J Rhinol Allergy. 2010 May-Jun;24(3):83-6. doi: 10.2500/ajra.2010.24.3482.
5
Histological and immunological features of non-eosinophilic nasal polyps.非嗜酸性鼻息肉的组织学和免疫学特征
Otolaryngol Head Neck Surg. 2007 Dec;137(6):925-30. doi: 10.1016/j.otohns.2007.07.036.
6
Correlation between middle turbinate and ipsilateral ethmoid histopathology in chronic rhinosinusitis.慢性鼻-鼻窦炎中中鼻甲与同侧筛窦组织病理学的相关性
Otolaryngol Head Neck Surg. 2006 Feb;134(2):250-4. doi: 10.1016/j.otohns.2005.10.023.
7
Update on the molecular biology of nasal polyposis.
Otolaryngol Clin North Am. 2005 Dec;38(6):1243-55. doi: 10.1016/j.otc.2005.08.010.
8
Site of origin of nasal polyps: relevance to pathogenesis and management.鼻息肉的起源部位:与发病机制及治疗的相关性
Rhinology. 2005 Sep;43(3):180-4.
9
Nasal polyposis: an update: editorial review.鼻息肉病:最新进展:编辑评论
Curr Opin Allergy Clin Immunol. 2003 Feb;3(1):1-6. doi: 10.1097/00130832-200302000-00001.
10
The estimated incidence of symptomatic nasal polyps.有症状鼻息肉的估计发病率。
Acta Otolaryngol. 2002 Mar;122(2):179-82. doi: 10.1080/00016480252814199.