Tanna Shrushti J, Anto Anandu M, Lovallo Victoria, Omoregie Eghosa, Khaja Misbahuddin
Internal Medicine, BronxCare Health System, Bronx, USA.
Medicine, BronxCare Health System, Bronx, USA.
Cureus. 2024 Dec 31;16(12):e76665. doi: 10.7759/cureus.76665. eCollection 2024 Dec.
Dural venous sinus thrombosis (DVST) is characterized by thrombosis in the cerebral veins, the dural venous sinus, or both. Headache is the most common initial symptom. Patients can present with seizures, papilledema, focal neurological deficits, and mental status alteration. We describe a case of a young HIV-positive patient with a seizure disorder who presented with unrelenting headaches and breakthrough seizures and was diagnosed with thrombosis in the superior sagittal sinus extending to the left transverse and sigmoid sinuses with venous thrombosis in the left vein of Trolard. This case is highly relevant, reminding clinicians to keep a high index of suspicion for DVST in any patient with headache and neurological manifestations.
硬脑膜静脉窦血栓形成(DVST)的特征是脑静脉、硬脑膜静脉窦或两者均发生血栓形成。头痛是最常见的首发症状。患者可能出现癫痫发作、视乳头水肿、局灶性神经功能缺损和精神状态改变。我们描述了一例患有癫痫症的年轻HIV阳性患者,该患者出现持续性头痛和突破性癫痫发作,被诊断为上矢状窦血栓形成并延伸至左侧横窦和乙状窦,同时左侧Trolard静脉存在静脉血栓形成。该病例具有高度相关性,提醒临床医生对于任何有头痛和神经学表现的患者都要高度怀疑DVST。