Ferreira Efrem d'Avila, Hatta Mariko, Laymon Khin, Ikeda Izumi, Takeuchi Mizuki, Takeda Yasunaga, Morikawa Sakiko Yoshizawa, Horikawa Chika, Kato Noriko, Maegawa Hiroshi, Fujihara Kazuya, Sone Hirohito
Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty Medicine, 1-757 Asahimachi-dori, Chuoh-ku, Niigata951-8510, Japan.
Department of Health and Nutrition, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata950-3198, Japan.
Public Health Nutr. 2025 Feb 4;28(1):e49. doi: 10.1017/S136898002500014X.
To evaluate the association between dietary fibre intake and obesity in Japanese outpatients with type 2 diabetes, as well as the demographic and dietary factors influencing this association.
Cross-sectional study with nationwide registry data on Japanese type 2 diabetes outpatients (2014–2019). Diet was self-reported via a FFQ. Obesity was defined as BMI ≥ 25 kg/m.
Clinics throughout Japan.
1565 Japanese outpatients with type 2 diabetes (63·1 % men; age range 30–89 years).
Multivariate analysis revealed that a higher dietary fibre intake was associated with a lower risk of obesity in all participants (95 % CI = 0·439, 0·795, trend = 0·002). Stratified analysis showed a significant inverse association between fibre intake and obesity in men and the older age groups (59–89 years), but not in women or the younger age group (30–58 years). In men, higher fibre intake was associated with healthier lifestyle behaviours, including increased physical activity ( < 0·001) and non-smoking ( < 0·001), with stronger associations compared with women. Vegetables, fruits and soyabeans/soya products were strongly correlated with fibre, while grains had a weak correlation. Folate was the micronutrient most strongly correlated with fibre.
Higher fibre intake was associated with lower obesity risk, particularly in men and older age groups. These findings emphasise the need for targeted public health initiatives promoting the intake of diverse fibre-rich foods to effectively manage obesity. Further research is needed to understand sex- and age-specific factors in the fibre–obesity relationship in diverse populations.
评估日本2型糖尿病门诊患者膳食纤维摄入量与肥胖之间的关联，以及影响这种关联的人口统计学和饮食因素。
对日本2型糖尿病门诊患者（2014 - 2019年）的全国登记数据进行横断面研究。饮食通过食物频率问卷自我报告。肥胖定义为体重指数（BMI）≥25 kg/m²。
日本各地的诊所。
1565名日本2型糖尿病门诊患者（男性占63.1%；年龄范围30 - 89岁）。
多变量分析显示，所有参与者中，较高的膳食纤维摄入量与较低的肥胖风险相关（95%置信区间 = 0.439, 0.795，趋势 = 0.002）。分层分析表明，男性和老年组（59 - 89岁）的纤维摄入量与肥胖之间存在显著的负相关，而女性或年轻组（30 - 58岁）则不存在。在男性中，较高的纤维摄入量与更健康的生活方式行为相关，包括增加体力活动（P < 0.001）和不吸烟（P < 0.001），与女性相比关联更强。蔬菜、水果和大豆/豆制品与纤维密切相关，而谷物的相关性较弱。叶酸是与纤维相关性最强的微量营养素。
较高的纤维摄入量与较低的肥胖风险相关，尤其是在男性和老年组中。这些发现强调了有针对性的公共卫生举措的必要性，以促进摄入各种富含纤维的食物，从而有效控制肥胖。需要进一步研究以了解不同人群中纤维与肥胖关系的性别和年龄特异性因素。
