Velázquez-López Arturo Alberto, Torres-Gregorio Margarita, García-Rojas Vanessa, Hernández-Sánchez Humberto, Mora-Escobedo Rosalva
Instituto Politécnico Nacional, ENCB, Campus Zacatenco. Miguel Othón de Mendizábal 699, Alcaldía G.A. Madero, Ciudad de México, CDMX, México, C.P. 07360, México.
Plant Foods Hum Nutr. 2025 Feb 4;80(1):55. doi: 10.1007/s11130-025-01299-7.
Aloe barbadensis is a natural source of bioactive compounds whose combined effects have been linked to the improvement of several diseases. There is scientific evidence obtained through in vitro and in vivo assays showing the possible benefits of aloe gel. The aim of this research was to characterize and determine the in vitro antioxidant, anti-inflammatory, antihypertensive and antibacterial capacities of aloe gel extract. The gel was extracted by removing the exocarp of aloe leaves. Physicochemical characterization, antioxidant activity, quantification of phenolic compounds, spectroscopic techniques (Fourier Transform Infrared (FTIR), Raman, XPS and XRD) and in vitro biological activities were then performed. The aloe gel contained 66.95% of polysaccharides, corresponding to dietary fiber. FTIR and Raman spectroscopy revealed bands of functional groups (e.g., COO-, CO-, and OH) related to the structure of polymannans. X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD) analyses revealed the presence of minerals such as manganese, magnesium, molybdenum, potassium, sodium, and cobalt. The phenolic compounds identified by HPLC were diverse, highlighting the presence of aloe emodin, aloin and gallic acid. The aloe gel exhibited anti-inflammatory, antihypertensive and antibacterial (Salmonella Typhi, Escherichia coli and Staphylococcus aureus) activities, indicating the possible use of Aloe barbadensis M. as a therapeutic agent for the treatment of diseases.
库拉索芦荟是生物活性化合物的天然来源，其综合作用与多种疾病的改善有关。通过体外和体内试验获得的科学证据表明了芦荟凝胶可能具有的益处。本研究的目的是表征和测定芦荟凝胶提取物的体外抗氧化、抗炎、降压和抗菌能力。通过去除芦荟叶的外皮来提取凝胶。然后进行了物理化学表征、抗氧化活性、酚类化合物定量、光谱技术（傅里叶变换红外光谱（FTIR）、拉曼光谱、X射线光电子能谱（XPS）和X射线衍射（XRD））以及体外生物活性研究。芦荟凝胶含有66.95%的多糖，相当于膳食纤维。FTIR和拉曼光谱揭示了与聚甘露糖结构相关的官能团（如COO-、CO-和OH）的谱带。X射线光电子能谱（XPS）和X射线衍射（XRD）分析揭示了锰、镁、钼、钾、钠和钴等矿物质的存在。通过高效液相色谱法鉴定的酚类化合物种类多样，突出显示了芦荟大黄素、芦荟素和没食子酸的存在。芦荟凝胶表现出抗炎、降压和抗菌（伤寒沙门氏菌、大肠杆菌和金黄色葡萄球菌）活性，表明库拉索芦荟可能作为治疗疾病的治疗剂。
