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新型肥胖药物对体重歧视和社会态度的影响:一项叙述性综述。

The Impact of Novel Medications for Obesity on Weight Stigma and Societal Attitudes: A Narrative Review.

作者信息

Heitmann Berit L

机构信息

Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark.

Section for General Practise, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

出版信息

Curr Obes Rep. 2025 Feb 5;14(1):18. doi: 10.1007/s13679-025-00611-5.

Abstract

PURPOSE OF REVIEW

This narrative review examines the potential implications of the expanded use of novel medications for obesity, particularly the GLP-1 receptor agonists, on weight stigma and societal attitudes towards pharmacologically induced weight loss. It analyses how these medications may potentially contribute to both reducing and exacerbating stigma and discusses strategies to reduce weight bias.

RECENT FINDINGS

The introduction of GLP-1 receptor agonists has demonstrated effectiveness in reducing weight and lead to improved health outcomes for individuals living with obesity. However, while these medications may reduce stigma by framing obesity as a medical issue rather than a personal failure, disparities in access and use related to high costs may inflate existing biases against those who cannot afford treatment. Also, a few studies indicate that users of these medications may feel stigmatised for taking what is perceived as an "easy way out" to lose weight, mirroring historical attitudes towards bariatric surgery. The new medications for obesity may have the potential to reduce obesity stigma by reframing it as a medical condition rather than a moral failing. However, taking legal actions to build a more inclusive society including ensuring equitable access to these medications will be essential in mitigating stigma and help fostering a supportive environment for those living with obesity. Lessons from reducing stigma surrounding other medical conditions suggest that supportive health care and educational campaigns that promote the understanding of obesity as a complex health issue are needed to reshape negative perceptions towards individuals with obesity.

摘要

综述目的

本叙述性综述探讨了新型肥胖药物(尤其是胰高血糖素样肽-1受体激动剂)的广泛使用对体重歧视以及社会对药物诱导减肥态度的潜在影响。它分析了这些药物如何可能既有助于减少又可能加剧歧视,并讨论了减少体重偏见的策略。

最新发现

胰高血糖素样肽-1受体激动剂的引入已证明在减轻体重方面有效,并改善了肥胖患者的健康状况。然而,虽然这些药物可能通过将肥胖视为一个医学问题而非个人失败来减少歧视,但与高成本相关的获取和使用差异可能会加剧现有的对那些负担不起治疗费用者的偏见。此外,一些研究表明,这些药物的使用者可能会因采取被视为“轻松减肥”的方式而感到受到歧视,这反映了历史上对减肥手术的态度。新型肥胖药物可能有潜力通过将肥胖重新定义为一种医学状况而非道德缺陷来减少肥胖歧视。然而,采取法律行动建设一个更具包容性的社会,包括确保公平获取这些药物,对于减轻歧视以及帮助为肥胖者营造一个支持性环境至关重要。从减少围绕其他疾病的歧视中吸取的教训表明,需要开展支持性的医疗保健和教育活动,促进将肥胖理解为一个复杂的健康问题,以重塑对肥胖者的负面看法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89ac/11799028/14d0c7a967da/13679_2025_611_Fig1_HTML.jpg

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