前列环素对哮喘患者抗原诱导的速发型支气管收缩的影响。
Effect of prostacyclin on antigen induced immediate bronchoconstriction in asthmatic patients.
作者信息
Bianco S, Robuschi M, Grugni A, Ceserani R, Gandolfi C
出版信息
Prostaglandins Med. 1979 Jul;3(1):39-45. doi: 10.1016/0161-4630(79)90014-4.
PMID:399527
Abstract
The effect of premedication with inhaled prostacyclin (PGI2) on the allergen induced immediate bronchoconstriction was investigated in 10 asthmatic patients, under single blind conditions, by means of a body plethysmograph. Statistical analysis (Dunnett's test) did not show any significant difference between PGI2 and placebo. The possible meaning of these results is discussed.
摘要
在10名哮喘患者中，采用体容积描记法，在单盲条件下研究了吸入前列环素（PGI2）预处理对变应原诱发的速发型支气管收缩的影响。统计分析（Dunnett检验）显示PGI2与安慰剂之间无显著差异。并对这些结果的可能意义进行了讨论。
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