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膀胱孤立性纤维瘤:老年男性患者的诊断挑战与手术治疗,病例报告及文献综述

Solitary fibrous tumor of the bladder: Diagnostic challenges and surgical management in an elderly male, a case report and literature review.

作者信息

Ibrahimi Ahmed, Tariqi Reda, Mikou Mohammed Ali, Boualaoui Imad, El Sayegh Hachem, Nouini Yassine

机构信息

Department of Urologic Surgery "A" Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

Department of Urologic Surgery "A" Ibn Sina University Hospital, Mohammed V University, Rabat, Morocco.

出版信息

Int J Surg Case Rep. 2025 Mar;128:111053. doi: 10.1016/j.ijscr.2025.111053. Epub 2025 Feb 12.

Abstract

INTRODUCTION

Solitary fibrous tumors (SFTs) of the bladder are rare mesenchymal neoplasms that mimic other bladder tumors, requiring a multidisciplinary approach for diagnosis and management.

CASE PRESENTATION

An 81-year-old male with a 30-pack-year smoking history presented with clotting hematuria and acute renal failure. Imaging revealed a large bladder mass causing bilateral ureteral obstruction. Transurethral resection and immunohistochemical analysis confirmed an SFT. The patient underwent cystoprostatectomy with Bricker diversion, achieving full recovery.

DISCUSSION

Bladder SFTs are often misdiagnosed as other spindle cell tumors. Histopathology and CD34 immunopositivity are key for diagnosis. Although typically benign, recurrence and metastasis require long-term follow-up.

CONCLUSION

This case underscores the rarity of bladder SFTs and highlights the importance of accurate diagnosis and complete surgical excision for optimal outcomes.

摘要

引言

膀胱孤立性纤维瘤(SFTs)是罕见的间质性肿瘤,易与其他膀胱肿瘤混淆,需要多学科方法进行诊断和管理。

病例报告

一名有30年吸烟史、81岁的男性患者,出现凝血性血尿和急性肾衰竭。影像学检查显示膀胱有一个大肿块,导致双侧输尿管梗阻。经尿道切除术及免疫组化分析确诊为SFT。患者接受了膀胱前列腺切除术及Bricker尿流改道术,实现了完全康复。

讨论

膀胱SFT常被误诊为其他梭形细胞瘤。组织病理学检查及CD34免疫阳性是诊断的关键。虽然通常为良性,但复发和转移需要长期随访。

结论

本病例强调了膀胱SFT的罕见性,并突出了准确诊断和完整手术切除以获得最佳结果的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4986/11871476/df02dac37701/gr1.jpg

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