Marshall J B, Eckhauser M L
Dig Dis Sci. 1985 Jun;30(6):582-7. doi: 10.1007/BF01320267.
A 36-year-old man, followed for 14 years with recurrent abdominal pain, developed chronic calcific pancreatitis and was found to have pancreas divisum on endoscopic retrograde pancreatography. An intraoperative biopsy showed normal acinar tissue in the head of the pancreas, while the body and tail were replaced by fibrous tissue. His pain resolved following surgical drainage of the dorsal pancreatic duct. Evaluation of the clinical course of this patient and critical review of other such cases in the literature support the role of compromised ductal drainage of the dorsal pancreas in the pathogenesis of chronic pancreatitis in pancreas divisum.
一名36岁男性,因反复腹痛接受随访14年,发展为慢性钙化性胰腺炎,经内镜逆行胰胆管造影发现胰腺分裂。术中活检显示胰头腺泡组织正常,而胰体和胰尾被纤维组织取代。经背侧胰管手术引流后,他的疼痛缓解。对该患者临床病程的评估以及对文献中其他此类病例的严格审查支持了背侧胰腺导管引流受损在胰腺分裂所致慢性胰腺炎发病机制中的作用。