Peters John D, Salame Nicole, Eber Ariel, Labadie Jessica G, Kandula Prasanthi, Dover Jeffrey S
Bryn Mawr Dermatology, Villanova, Pennsylvania.
SkinCare Physicians, Chestnut Hill, Massachusetts.
Dermatol Surg. 2025 Feb 18;51(7):684-689. doi: 10.1097/DSS.0000000000004584.
Facial aging, marked by skin laxity, wrinkling, and dyspigmentation, remains a common aesthetic concern. Few studies have investigated combination approaches to treat these concomitant components of aging.
To investigate the effect of combining monopolar radiofrequency with fractional nonablative diode laser treatments to improve skin laxity, wrinkling, and dyspigmentation.
A prospective, single-arm study enrolled 20 females with mild to moderate facial skin laxity and photoaging. Subjects underwent a sequence of one monopolar radiofrequency treatment (Thermage FLX, Solta, Bausch Medica, Bothell, WA) followed by 4 fractional 1440-/1927-nm nonablative diode laser treatments (Clear + Brilliant Touch, Solta, Bausch Medica). Assessments included clinical evaluations, blinded photographic assessments, and patient satisfaction scores.
At the 6-month follow-up, a significant improvement was observed in Skin Laxity Grading Scale and Glogau Classification of Photoaging scale scores (1.65 ± 0.49-1.30 ± 0.47, p = .039, and 1.85 ± 0.36-1.35 ± 0.49, p = .00082, respectively). Blinded reviewers correctly identified 67% of post-treatment photographs, and 77% of participants were considered responders. No serious adverse events occurred.
Monopolar radiofrequency combined with fractional diode led to significant efficacy, suggesting a safe and promising strategy for addressing facial skin laxity, wrinkles, and dyspigmentation.
面部老化表现为皮肤松弛、皱纹和色素沉着,仍是常见的美学问题。很少有研究探讨联合治疗这些伴随出现的老化因素的方法。
研究单极射频联合非剥脱性分数二极管激光治疗改善皮肤松弛、皱纹和色素沉着的效果。
一项前瞻性单臂研究纳入了20名有轻度至中度面部皮肤松弛和光老化的女性。受试者先接受一次单极射频治疗(Thermage FLX,索塔公司,博士伦医疗,华盛顿州博塞尔),随后进行4次非剥脱性1440/1927纳米分数二极管激光治疗(Clear + Brilliant Touch,索塔公司,博士伦医疗)。评估包括临床评估、盲法照片评估和患者满意度评分。
在6个月的随访中,皮肤松弛分级量表和光老化Glogau分类量表评分有显著改善(分别从1.65±0.49降至1.30±0.47,p = 0.039;从1.85±0.36降至1.35±0.49,p = 0.00082)。盲法评审者正确识别了67%的治疗后照片,77%的参与者被视为有反应者。未发生严重不良事件。
单极射频联合分数二极管治疗有显著疗效,提示这是一种解决面部皮肤松弛、皱纹和色素沉着的安全且有前景的策略。