Jung Dong Hoon, Nam Gi Moon, Lee Chang Kyun, Kim Chul Hong, Lim Hyun-San, Lee Ji Yeon, Lim Hee-Sook
Department of Gerontology, AgeTech-Service Convergence Major, Graduate School of East-West Medical Science, Kyung Hee University, Yongin 17104, Korea.
Center for Crohn's and Colitis, Department of Gastroenterology, Kyung Hee University College of Medicine, Seoul 02447, Korea.
Clin Nutr Res. 2025 Feb 5;14(1):30-40. doi: 10.7762/cnr.2025.14.1.30. eCollection 2025 Jan.
This study was conducted to evaluate changes in hydrogen breath test results and nutritional improvements when Korean adults diagnosed with lactose intolerance consumed processed milk containing approximately 10 g of lactose continuously. Participants consumed 240 mL of intervention food daily for a month and visited the research institute before and after the intervention to undergo nutrient intake survey and hydrogen breath tests. Data from 32 participants, with a mean age of 52.9 years, were analyzed. Hydrogen breath tests showed a significant decrease in hydrogen levels at all but baseline and the first of five 20-minute intervals of expiratory hydrogen concentration measurements. The third and fourth measurements showed the most significant changes (p < 0.001). The gastrointestinal symptoms showed a decreasing trend. Nutrient intake analysis demonstrated significant increases in animal protein (p < 0.001), calcium (p < 0.001), percentage of energy from protein (p = 0.032), vitamin A (p = 0.032), and retinol levels (p = 0.023). Regarding dietary habits, significant improvements were observed in nutritional quotient variables, including nutritional score (p = 0.042) and balance (p = 0.034). This study suggests that the removal of lactose and dairy products is not necessary for individuals with lactose intolerance. Incorporating low-lactose processed milk into their usual diet might be a practical dietary management strategy.
本研究旨在评估被诊断为乳糖不耐受的韩国成年人持续饮用含有约10克乳糖的加工牛奶时,呼氢试验结果的变化以及营养状况的改善情况。参与者连续一个月每天饮用240毫升干预食品,并在干预前后前往研究所进行营养摄入调查和呼氢试验。对32名平均年龄为52.9岁的参与者的数据进行了分析。呼氢试验显示,除了基线以及呼气氢浓度测量的五个20分钟间隔中的第一个间隔外,其他所有间隔的氢水平均显著下降。第三次和第四次测量显示出最显著的变化(p < 0.001)。胃肠道症状呈下降趋势。营养摄入分析表明,动物蛋白(p < 0.001)、钙(p < 0.001)、蛋白质能量百分比(p = 0.032)、维生素A(p = 0.032)和视黄醇水平(p = 0.023)均显著增加。在饮食习惯方面,营养商数变量,包括营养得分(p = 0.042)和平衡度(p = 0.034)有显著改善。本研究表明,对于乳糖不耐受的个体,无需去除乳糖和乳制品。将低乳糖加工牛奶纳入其日常饮食可能是一种切实可行的饮食管理策略。