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简化烧伤严重程度指数与严重烧伤患者死亡率的关联:一项荟萃分析。

Association of the abbreviated burn severity index with mortality in severely burned patients: A meta-analysis.

作者信息

Deng Guangrong, Tang Ling, Yang Qian, Li Zhengyong

机构信息

Department of Anesthesiology, West China Hospital, Sichuan University/West China School of Nursing Sichuan University, Chengdu, Sichuan, China.

Department of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu, China.

出版信息

PLoS One. 2025 Feb 20;20(2):e0319199. doi: 10.1371/journal.pone.0319199. eCollection 2025.

Abstract

BACKGROUND AND PURPOSE

The ability of the abbreviated burn severity index (ABSI) to predict death among patients with severe burns remains unclear. This meta-analysis aimed to identify the association between the ABSI and mortality in severely burned patients.

METHODS

The PubMed, EMBASE and Web of Science databases were searched up to September 15, 2024. The odds ratios (ORs) with 95% confidence intervals (CIs) were combined, and a subgroup analysis was conducted on the basis of age, ABSI grouping method and OR source. All the statistical analyses were performed with STATA version 15.0.

RESULTS

Sixteen studies with 4011 cases were included in the analysis. The pooled results demonstrated that an elevated ABSI was significantly related to an increased risk of mortality (OR = 1.72, 95% CI: 1.48-2.00; P < 0.001). In addition, subgroup analysis by age (adult: OR = 1.35, P < 0.001; child: OR = 68.40, P < 0.001), ABSI grouping method (dichotomous: OR = 16.14, P < 0.001; continuous: OR = 1.59, P < 0.001) and OR source (univariate: OR = 11.42, P = 0.015; multivariate: OR = 1.51, P < 0.001) yielded similar results.

CONCLUSION

The ABSI serves as a reliable prognostic indicator in severely burned patients, and patients with an elevated ABSI are at increased risk of death.

摘要

背景与目的

简化烧伤严重程度指数(ABSI)预测重度烧伤患者死亡的能力尚不清楚。本荟萃分析旨在确定ABSI与重度烧伤患者死亡率之间的关联。

方法

检索截至2024年9月15日的PubMed、EMBASE和Web of Science数据库。合并95%置信区间(CI)的比值比(OR),并根据年龄、ABSI分组方法和OR来源进行亚组分析。所有统计分析均使用STATA 15.0版进行。

结果

纳入分析的有16项研究,共4011例病例。汇总结果表明,ABSI升高与死亡风险增加显著相关(OR = 1.72,95%CI:1.48 - 2.00;P < 0.001)。此外,按年龄(成人:OR = 1.35,P < 0.001;儿童:OR = 68.40,P < 0.001)、ABSI分组方法(二分法:OR = 16.14,P < 0.001;连续变量法:OR = 1.59,P < 0.001)和OR来源(单变量:OR = 11.42,P = 0.015;多变量:OR = 1.51,P < 0.001)进行的亚组分析得出了类似结果。

结论

ABSI是重度烧伤患者可靠的预后指标,ABSI升高的患者死亡风险增加。

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