Soumekh Lisa, Bell Samantha, Espinosa Sandra L, Grogan Tristan, Kesavan Kalpashri, Calkins Kara L
Department of Pediatrics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Department of Medicine Statistics Core, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
J Perinatol. 2025 Feb 21. doi: 10.1038/s41372-024-02207-8.
We aimed to characterize general movements in neonates with congenital gastrointestinal anomalies and to compare them to general movements in extremely low birth weight (ELBW) infants.
This was a retrospective, single-site study. Subjects were divided into two groups: those with gastrointestinal (GI) anomalies and ELBW infants (birth weight <1 kg). The primary outcome was general movement assessments.
Ninety-six infants were included (n = 51, GI group and n = 45, ELBW group). The rates of abnormal general movements between the groups were comparable (writhing movements: 61% vs. 59%, p = 0.89; fidgety movements: 20% vs. 36%, p = 0.13). Writhing movements were different (100% poor repertoire, 0% cramped synchronous in the GI group vs. 50% poor repertoire and 50% cramped synchronous in the ELBW group, p < 0.001).
Infants with gastrointestinal anomalies are at risk for abnormal general movements. Abnormal fidgety general movements may be an early biomarker for future motor deficits.
我们旨在描述患有先天性胃肠道异常的新生儿的一般运动特征，并将其与极低出生体重（ELBW）婴儿的一般运动进行比较。
这是一项回顾性单中心研究。受试者分为两组：患有胃肠道（GI）异常的婴儿和ELBW婴儿（出生体重<1千克）。主要结局是一般运动评估。
纳入了96名婴儿（n = 51，GI组；n = 45，ELBW组）。两组之间异常一般运动的发生率相当（扭动运动：61%对59%，p = 0.89；不安运动：20%对36%，p = 0.13）。扭动运动有所不同（GI组中100%为动作模式差，0%为痉挛同步；ELBW组中50%为动作模式差，50%为痉挛同步，p < 0.001）。
患有胃肠道异常的婴儿存在一般运动异常的风险。异常的不安一般运动可能是未来运动功能缺陷的早期生物标志物。
