Guru Siddartha, Guru Navami, Hussein Rezhan
Infectious Disease, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA.
Internal Medicine, Greater Baltimore Medical Center, Towson, MD, USA.
IDCases. 2025 Jan 27;39:e02168. doi: 10.1016/j.idcr.2025.e02168. eCollection 2025.
Emphysematous osteomyelitis is a rare entity that characteristically presents with intraosseous gas and positive bone cultures with gas-forming bacteria. We present a case of a 63-year-old woman who presented with lower back pain, decreased appetite, and unintentional weight loss over three weeks. Thoracic spine Computerized tomography image showed an ill-defined lytic lesion containing gas in the T12 vertebral body with anaerobic bone cultures, which grew There was concern for possible complication of meningitis with abnormal CSF studies but no bacterial growth, though lumber puncture was done after being on antibiotics for five days. She was found to have underlying metastatic colon cancer as well. She was treated with six weeks of ceftriaxone and metronidazole and then transitioned to oral amoxicillin-clavulanic acid while on chemotherapy.
气性骨髓炎是一种罕见的病症，其典型表现为骨内气体以及骨培养结果显示有产气细菌生长。我们报告一例63岁女性病例，该患者在三周内出现下背部疼痛、食欲减退和体重意外减轻。胸椎计算机断层扫描图像显示，T12椎体有一个边界不清的溶骨性病变，内含气体，厌氧骨培养结果显示有细菌生长。尽管在使用抗生素五天后进行了腰椎穿刺，但脑脊液检查异常，担心可能并发脑膜炎，但未发现细菌生长。同时发现她还患有潜在的转移性结肠癌。她接受了六周的头孢曲松和甲硝唑治疗，然后在化疗期间转为口服阿莫西林 - 克拉维酸。
