Abraham Andrew T, Padam Sripal
Internal Medicine, University of Central Florida College of Medicine, Graduate Medical Education/Hospital Corporation of America (HCA) Florida, North Florida Hospital, Gainesville, USA.
Cureus. 2023 Sep 16;15(9):e45343. doi: 10.7759/cureus.45343. eCollection 2023 Sep.
Colon cancer is one of the leading causes of morbidity and mortality throughout the world. Some of the most common presenting signs are a change in bowel habits, alteration of fecal contour or consistency, blood in stool, fatigue, and weight loss. However, it may present insidiously. This is the case of an 81-year-old female with bacteremia as the primary presenting sign of metastatic colon cancer. In further literature review, we discuss the genomic associations that contribute to the severity of the disease and explore the potential links between the gut microbiome and colorectal carcinoma. This article highlights risk factor modifications and lab abnormalities that may be useful for the primary care provider and acute care practitioner.
结肠癌是全球发病和死亡的主要原因之一。一些最常见的症状包括排便习惯改变、粪便外形或质地改变、便血、疲劳和体重减轻。然而，其症状可能隐匿出现。本文报道了一位81岁女性，以菌血症作为转移性结肠癌的主要首发症状。在进一步的文献综述中，我们讨论了导致疾病严重程度的基因组关联，并探讨了肠道微生物群与结直肠癌之间的潜在联系。本文重点介绍了可能对初级保健提供者和急症护理从业者有用的风险因素改变和实验室异常情况。
