Sleigh Jamie W
Department of Anaesthesia and Pain Medicine, Waikato Clinical School, University of Auckland, Hamilton, New Zealand.
Br J Anaesth. 2025 Apr;134(4):898-899. doi: 10.1016/j.bja.2025.01.002. Epub 2025 Feb 21.
Compared with the young, the older patient group has increased high-frequency EEG power whilst under volatile general anaesthesia. This increased high-frequency power elevates the spectral entropy values above the recommended range. Thus, aggressive titration of general anaesthesia with volatile agents to achieve entropy values of 40-60 in older patients will commonly result in overdose, as manifest by burst suppression.
与年轻患者相比,老年患者组在挥发性全身麻醉下高频脑电图功率增加。这种增加的高频功率使频谱熵值升高到推荐范围之上。因此,在老年患者中积极滴定挥发性麻醉剂以达到40 - 60的熵值通常会导致过量,表现为爆发抑制。