Zhang Han, Yang Kuiliang, Yang Wanju, Wan Shanshan, Yang Yanning, Xing Yiqiao
Eye Center, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Department of Ophthalmology, Aier Eye Hospital of Wuhan University, Wuhan, Hubei, China.
J Curr Ophthalmol. 2025 Jan 18;36(2):159-167. doi: 10.4103/joco.joco_46_24. eCollection 2024 Apr-Jun.
To investigate the epidemiological characteristics of dry eye disease (DED) in Asian populations and among females.
This study utilized the literature-derived database on DED risk factors, which includes data from 119 studies, and followed an evidence-based medicine retrieval strategy, searching globally for studies on risk factors for DED. Specifically, we focused on the Asian and Asian female populations. A descriptive statistical analysis was conducted on the definitions and prevalence of DED as provided in the database.
The study included a total of 139,556 participants, of which 74,258 were females. The overall prevalence of DED in Asians was found to be 23.9%, and it was observed to increase with age. Specifically, the prevalence was 16.2% in the group aged <30 years, and it increased to 26.7% in the group aged over 70 years. Among females, the prevalence of DED was higher at 28.1% compared to males at 20.1%. Furthermore, the prevalence of DED in females also increased with age, ranging from 39.9% in the group aged <40 years to 42.2% in the group aged over 60 years. The prevalence of DED between 2016 and 2022 was 35.3%, which indicated a significant increase of 14.6% compared to the period between 2008 and 2015. Notably, there were variations in the prevalence of DED across different regions and levels of development.
This study reveals a common occurrence of DED among Asians and women. The prevalence rates vary among different countries, regions, development levels, and sample sizes, and there is an observed upward trend with the increase in survey year and age.
调查亚洲人群及女性中干眼疾病（DED）的流行病学特征。
本研究利用了关于DED危险因素的文献数据库，该数据库包含119项研究的数据，并遵循循证医学检索策略，在全球范围内搜索关于DED危险因素的研究。具体而言，我们重点关注亚洲和亚洲女性人群。对数据库中提供的DED定义和患病率进行了描述性统计分析。
该研究共纳入139,556名参与者，其中女性74,258名。亚洲人DED的总体患病率为23.9%，且随年龄增长而增加。具体而言，<30岁组的患病率为16.2%，70岁以上组则增至26.7%。在女性中，DED的患病率更高，为28.1%，而男性为20.1%。此外，女性中DED的患病率也随年龄增长，从<40岁组的39.9%到60岁以上组的42.2%不等。2016年至2022年期间DED的患病率为35.3%，与2008年至2015年期间相比显著增加了14.6%。值得注意的是，不同地区和发展水平的DED患病率存在差异。
本研究揭示了亚洲人和女性中DED的普遍存在。不同国家、地区、发展水平和样本量的患病率各不相同，且随着调查年份和年龄的增加呈现上升趋势。
