Zhou Qianru, Wang Yujie, Si Guangxiang, Chen Xingbiao, Mu Dan, Zhang Bing
Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210008, China.
Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing 210008, China.
Chem Biomed Imaging. 2025 Jan 21;3(2):51-76. doi: 10.1021/cbmi.4c00064. eCollection 2025 Feb 24.
Atherosclerosis (AS) is a serious disease that poses a significant threat to the global population. In this review, we analyze the development of AS from multiple perspectives, aiming to elucidate its molecular mechanisms. We also focus on imaging techniques and therapeutic approaches, highlighting the crucial role of nanomaterials in both imaging and therapy for AS. By leveraging their compatibility and targeting capabilities, nanomaterials can be integrated with traditional medical imaging and therapeutic agents to achieve targeted drug delivery, controlled release, and precise localization and imaging of atherosclerotic plaques.
动脉粥样硬化（AS）是一种对全球人口构成重大威胁的严重疾病。在本综述中，我们从多个角度分析AS的发展，旨在阐明其分子机制。我们还关注成像技术和治疗方法，强调纳米材料在AS成像和治疗中的关键作用。通过利用其相容性和靶向能力，纳米材料可以与传统医学成像和治疗剂相结合，实现靶向药物递送、控释以及动脉粥样硬化斑块的精确定位和成像。
