Ding Luoyang, Wang Yifan, Zhang Linna, Luo Chengfang, Wu Feifan, Huang Yiming, Zhen Yongkang, Chen Ning, Wang Limin, Song Li, Pool Kelsey, Blache Dominique, Maloney Shane K, Liu Dongxu, Yang Zhiquan, Huang Xiaoyan, Li Chuang, Yu Xiang, Zhang Zhenbin, Chen Yifei, Xue Chun, Gu Yalan, Huang Weidong, Yan Lu, Wei Wenjun, Wang Yusu, Zhang Jinying, Zhang Yifan, Sun Yiquan, Dai Rui, Wang Shengbo, Zhao Xinle, Wang Haodong, Zhou Ping, Yang Qing-Yong, Wang Mengzhi
Laboratory of Metabolic Manipulation of Herbivorous Animal Nutrition, College of Animal Science and Technology Yangzhou University Yangzhou China.
State Key Laboratory of Sheep Genetic Improvement and Healthy Production Xinjiang Academy of Agricultural Reclamation Sciences Shihezi China.
Imeta. 2025 Jan 28;4(1):e267. doi: 10.1002/imt2.267. eCollection 2025 Feb.
Here, we describe the Herbivore Transcriptome Integrated Resource Database (HTIRDB, https://yanglab.hzau.edu.cn/HTIRDB#/). The HTIRDB comprises the self-generated transcriptomic data from 100 to 105 tissues from two female domestic herbivores from six species (cattle, donkey, goat, horse, rabbit, and sika deer) and two breeds of sheep, and an extra 28,710 related published datasets. The HTIRDB user-friendly interface provides tools and functionalities that facilitate the exploration of gene expression between tissues and species. The tools for comparative transcriptomics can be used to identify housekeeping genes, tissue-specific genes, species-specific genes, and species-conserved genes. To date, the HTIRDB is the most extensive transcriptome data resource for domestic herbivores that is freely available.