多发性硬化症中的焦虑与认知：一项叙述性综述
Anxiety and Cognition in Multiple Sclerosis: A Narrative Review.
作者信息
Susini Roberto Martin, Ciufia Natalia, Marinangeli Aldana Lucía, Alonso Ricardo, Eizaguirre María Bárbara
机构信息
From the Demyelinating Diseases Working Group (CUEM), Neurology Division, Ramos Mejía Hospital, Buenos Aires, Argentina.
Research Institute in Psychology, School of Psychology, Buenos Aires University, Buenos Aires, Argentina.
出版信息
Int J MS Care. 2025 Mar 3;27(Q1):63-73. doi: 10.7224/1537-2073.2024-037. eCollection 2025 Jan.
BACKGROUND
People with multiple sclerosis (MS) often experience psychiatric symptoms, such as anxiety and depression, that impact disease progression and quality of life. Cognitive impairment, particularly in processing speed and episodic memory, is common in MS. There are several studies studying the relationship between anxiety and cognition in the population with MS. This study reviews that literature.
METHODS
This bibliographic review covers publications in Spanish and English from January 2006 to June 2022. It focuses on quantitative investigations of the relationship between anxiety symptoms and cognitive variables in people with MS.
RESULTS
A majority of studies found an association between anxiety and cognition in people with MS. Anxiety significantly affects information processing speed, learning, memory, attention, working memory, and verbal fluency in people with MS. However, some studies find no association. The impact of depressive symptoms and the bidirectional relationship between anxiety and cognition are highlighted.
CONCLUSIONS
Anxiety in people with MS is associated with cognitive impairment. Further research is needed to understand the mechanisms and establish causal relationships between anxiety and cognition in this population.
背景
多发性硬化症（MS）患者经常出现焦虑和抑郁等精神症状，这些症状会影响疾病进展和生活质量。认知障碍在MS患者中很常见，尤其是在处理速度和情景记忆方面。有几项研究探讨了MS患者中焦虑与认知之间的关系。本研究对相关文献进行综述。
方法
本文献综述涵盖了2006年1月至2022年6月期间以西班牙语和英语发表的文献。重点关注MS患者中焦虑症状与认知变量之间关系的定量研究。
结果
大多数研究发现MS患者中焦虑与认知之间存在关联。焦虑显著影响MS患者的信息处理速度、学习、记忆、注意力、工作记忆和言语流畅性。然而，一些研究未发现关联。强调了抑郁症状的影响以及焦虑与认知之间的双向关系。
结论
MS患者的焦虑与认知障碍有关。需要进一步研究以了解其机制，并在该人群中建立焦虑与认知之间的因果关系。
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